Abstract
A growing body of evidence has indicated that endophytic microorganism is one of the important prolific producers of natural products with potential application in new drug discovery. On the basis of the extensive literature search, new endophyte-related findings in secondary metabolites uncovered during the past 11 years (2006-2016) were summarized in this review according to their bioactive properties.
Keywords: Endophyte, symbiotic microbe, secondary metabolite, natural product, natural drug, drug lead.
The Natural Products Journal
Title:Bioactive Natural Products from Endophytic Microbes
Volume: 8 Issue: 2
Author(s): Huawei Zhang*, Xuelian Bai, Miao Zhang, Jianwei Chen and Hong Wang*
Affiliation:
- School of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014,China
- School of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014,China
Keywords: Endophyte, symbiotic microbe, secondary metabolite, natural product, natural drug, drug lead.
Abstract: A growing body of evidence has indicated that endophytic microorganism is one of the important prolific producers of natural products with potential application in new drug discovery. On the basis of the extensive literature search, new endophyte-related findings in secondary metabolites uncovered during the past 11 years (2006-2016) were summarized in this review according to their bioactive properties.
Export Options
About this article
Cite this article as:
Zhang Huawei *, Bai Xuelian , Zhang Miao , Chen Jianwei and Wang Hong *, Bioactive Natural Products from Endophytic Microbes, The Natural Products Journal 2018; 8 (2) . https://dx.doi.org/10.2174/2210315508666180103160508
DOI https://dx.doi.org/10.2174/2210315508666180103160508 |
Print ISSN 2210-3155 |
Publisher Name Bentham Science Publisher |
Online ISSN 2210-3163 |
Call for Papers in Thematic Issues
Recent Advances in Biotransformation of Bioactive Terpenoids using Aspergillus niger
Biotransformation is the reaction catalyzed by biological catalysts of either isolated enzymes or whole cell cultures of microorganisms. This process has been extensively applied in the conversion of bioactive terpenoids with high regio- and stereospecifity. This process has been also applied in the lead discovery and development. Aspergillus niger has ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Current Pathogenesis of Alzheimer’s Disease and Plants Derived Neuroprotective Phytoconstituents: A Comprehensive Review
Current Psychopharmacology Astrocytes: From the Physiology to the Disease
Current Alzheimer Research The Sphingolipid Rheostat: A Potential Target for Improving Pancreatic Islet Survival and Function
Endocrine, Metabolic & Immune Disorders - Drug Targets New Platinum and Ruthenium Complexes - the Latest Class of Potential Chemotherapeutic Drugs - a Review of Recent Developments in the Field
Mini-Reviews in Medicinal Chemistry Role of Estradiol and Progesterone in HIV Susceptibility and Disease Progression
Mini-Reviews in Medicinal Chemistry Bcl-2 Family Proteins Regulate Apoptosis and Epithelial to Mesenchymal Transition by Calcium Signals
Current Pharmaceutical Design Administration of Exogenous Surfactant and Cytosolic Phospholipase A2α Inhibitors may Help COVID-19 Infected Patients with Chronic Diseases
Coronaviruses Better Targeting Melanoma: Options Beyond Surgery and Conventional Chemotherapy
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery Diet-Derived Phytochemicals: From Cancer Chemoprevention to Cardio-Oncological Prevention
Current Drug Targets Allosteric Modulation of Protease-Activated Receptor Signaling
Mini-Reviews in Medicinal Chemistry Synthesis and In-Vitro Antitumor Activity of Selected 7-Fluoro-6-(4-methyl-1-piperazinyl)-2-(thiosubstituted)-4(3H)-quinazolinones
Letters in Organic Chemistry Effective Inhibition of Foam Cells Formation by Tanshinone IIA in RAW264.7 Macrophages Induced with LDL Isolated from Hypercholesterolemia Patients: A Proteomic Analysis
Current Proteomics Tackling Chronic Pain and Inflammation through the Purinergic System
Current Medicinal Chemistry Oxidative Stress, Pro-Inflammatory Cytokines, and Antioxidants Regulate Expression Levels of MicroRNAs in Parkinson’s Disease
Current Aging Science Patents on Immunotoxins and Chimeric Toxins for the Treatment of Cancer
Recent Patents on Drug Delivery & Formulation Targeting the EGFR-family for Therapy: Biological Challenges and Clinical Perspective
Current Pharmaceutical Design Crocetin, a Carotenoid Derivative, Inhibits VEGF-Induced Angiogenesis via Suppression of p38 Phosphorylation
Current Neurovascular Research Heme Oxygenase-1 in Tumor Biology and Therapy
Current Drug Targets Emergence of Ad-Mediated Combination Therapy Against Cancer: What to Expect?
Current Cancer Drug Targets Screening of Potential Anticancer Compounds from Sargassum wightii to Target Breast Cancer Specific HER2 Receptor using in-silico Analysis
The Natural Products Journal