Title:Novel Findings of Anti-cancer Property of Propofol
VOLUME: 18 ISSUE: 2
Author(s):Jiaqiang Wang, Chien-shan Cheng, Yan Lu, Xiaowei Ding, Minmin Zhu, Changhong Miao* and Jiawei Chen*
Affiliation:Department of Oncology, Shanghai Medical College, Fudan University, No. 270 DongAn Road, Shanghai 200032, Department of Oncology, Shanghai Medical College, Fudan University, No. 270 DongAn Road, Shanghai 200032, Department of Oncology, Shanghai Medical College, Fudan University, No. 270 DongAn Road, Shanghai 200032, Department of Oncology, Shanghai Medical College, Fudan University, No. 270 DongAn Road, Shanghai 200032, Department of Oncology, Shanghai Medical College, Fudan University, No. 270 DongAn Road, Shanghai 200032, Department of Oncology, Shanghai Medical College, Fudan University, No. 270 DongAn Road, Shanghai 200032, Department of Oncology, Shanghai Medical College, Fudan University, No. 270 DongAn Road, Shanghai 200032
Keywords:Propofol, anesthetic, general anesthesia, neoplasms, anti-cancer, malignance-modulating.
Abstract:Background: Propofol, a widely used intravenous anesthetic agent, is traditionally applied for sedation
and general anesthesia.
Explanation: Recent attention has been drawn to explore the effect and mechanisms of propofol against cancer
progression in vitro and in vivo. Specifically, the proliferation-inhibiting and apoptosis-inducing properties of
propofol in cancer have been studied. However, the underlying mechanisms remain unclear.
Conclusion: This review focused on the findings within the past ten years and aimed to provide a general overview
of propofol's malignance-modulating properties and the potential molecular mechanisms.
