Abstract
Combinatorial chemistry has contributed to the preparation of biologically important oligosaccharide and glycoconjugate libraries, with a view of improving our understanding of the complex interaction between the carbohydrates and their proteinbased receptors. The combinatorial carbohydrate synthesis strategies, developed in the past decade, provide access to small and medium size libraries. This mini review critically examines both the solution phase and solid phase strategies that have been reported to date.
Keywords: combinatorial chemistry, carbohydrates, solution phase synthesis, solid phase synthesis, glycoconjugates
Mini-Reviews in Organic Chemistry
Title: Combinatorial Carbohydrate Synthesis
Volume: 1 Issue: 1
Author(s): S. Nacak Baytas and R. J. Linhardt
Affiliation:
Keywords: combinatorial chemistry, carbohydrates, solution phase synthesis, solid phase synthesis, glycoconjugates
Abstract: Combinatorial chemistry has contributed to the preparation of biologically important oligosaccharide and glycoconjugate libraries, with a view of improving our understanding of the complex interaction between the carbohydrates and their proteinbased receptors. The combinatorial carbohydrate synthesis strategies, developed in the past decade, provide access to small and medium size libraries. This mini review critically examines both the solution phase and solid phase strategies that have been reported to date.
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Cite this article as:
Baytas Nacak S. and Linhardt J. R., Combinatorial Carbohydrate Synthesis, Mini-Reviews in Organic Chemistry 2004; 1 (1) . https://dx.doi.org/10.2174/1570193043488917
DOI https://dx.doi.org/10.2174/1570193043488917 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
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