Abstract
A series of sulfides was successfully synthesized from nitroarenes by SNAr reaction via elimination of a nitro or phenylsulfonyl group. The SNAr reaction mechanism is found to depend on the position and type of substituents, and the effect of two-electron withdrawing groups was also examined.
Keywords: Sulfide, SNAr reaction, nitro group, aryl disulfide.
Current Organic Synthesis
Title:Synthesis of Asymmetric Diaryl Sulfides by SNAr Reaction of Substituted Nitrobenzene with Aryl Disulfides
Volume: 10 Issue: 6
Author(s): Naoki Enjo, Rong Lu and Tetsuo Miyakoshi
Affiliation:
Keywords: Sulfide, SNAr reaction, nitro group, aryl disulfide.
Abstract: A series of sulfides was successfully synthesized from nitroarenes by SNAr reaction via elimination of a nitro or phenylsulfonyl group. The SNAr reaction mechanism is found to depend on the position and type of substituents, and the effect of two-electron withdrawing groups was also examined.
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Enjo Naoki, Lu Rong and Miyakoshi Tetsuo, Synthesis of Asymmetric Diaryl Sulfides by SNAr Reaction of Substituted Nitrobenzene with Aryl Disulfides, Current Organic Synthesis 2013; 10 (6) . https://dx.doi.org/10.2174/157017941006140206105221
DOI https://dx.doi.org/10.2174/157017941006140206105221 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
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Exploring the Role of Chemical Graph Theory in Advancing Current Organic Synthesis
Organic synthesis is a fundamental discipline in chemistry, crucial for the creation of complex molecules with diverse applications in pharmaceuticals, materials science, and beyond. However, the process of designing efficient synthetic routes for target molecules remains challenging. Chemical graph theory, a branch of theoretical chemistry, offers powerful tools for understanding ...read more
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