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Current Medicinal Chemistry


ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Review Article

An Overview of Synthetic Routes of Pharmaceutically Important Pyranopyrazoles

Author(s): Sarosh Iqbal*, Shumaila Kiran, Aliza Anwar, Shazia Abrar, Ansa Khalid, Mark G. Moloney and Muhammad N. Akhtar

Volume 29, Issue 41, 2022

Published on: 27 August, 2022

Page: [6288 - 6333] Pages: 46

DOI: 10.2174/0929867329666220714093848

Price: $65


Pyranopyrazoles are bicyclic nitrogen-containing heterocycles having broadspectrum bioactivities, which may act as anti-cancer, anti-inflammatory, antibacterial, antifungal, insecticidal and molluscicidal agents. Pyranopyrazoles have become an attractive scaffold for the discovery of new drugs due to the diverse range of bioactivities associated with this nucleus. In this review, we have focused on the medicinal importance of pyranopyrazole derivatives and highlighted different routes for the synthesis of pyranopyrazole derivatives using inexpensive and commonly available starting materials.

Keywords: Analgesic activity, anticancer activity, antimicrobial activity, insecticidal activity, molluscicidal activity, pyranopyrazole, synthesis.

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