Abstract
N-heterocyclic carbenes are extremely versatile ligands in homogeneous catalysis and coordination chemistry. A concurrent focus in this field is the construction of functionalized N-heterocyclic carbenes containing classical donor groups. The interest stems from the fact that multidentate ligand scaffolds can be finely constructed to fulfill specific purposes, such as providing extra-stability for metal complexes, possessing hemilability for effective generation of vacant coordination site, and allowing fine tuning of electronic and steric effects for inducing chemo-, stereo-, and enantioselectivities in catalytic reactions. There are numerous works on such multidentate ligands reported in the literature, in particular, those containing phosphorus, oxygen, and nitrogen functionalities. In this review, we will summarize the current development on functionalized N-heterocyclic carbenes in combination with classical donors of group 15 and 16 elements, illustrating typical preparations of the ligand precursors and their transition metal complexes. The coordination chemistry as well as catalytic applications of these ligands will be presented.
Keywords: Bidentate Ligands, N-Heterocyclic Carbene, Heck coupling reactions, deprotonation, pyridine-functionalized NHC ligands
Current Organic Chemistry
Title: Recent Development of Functionalized N-heterocyclic Carbene Ligands:Coordination Chemistry and Catalytic Applications
Volume: 11 Issue: 17
Author(s): Hon Man Lee, Chun-Chin Lee and Pi-Yun Cheng
Affiliation:
Keywords: Bidentate Ligands, N-Heterocyclic Carbene, Heck coupling reactions, deprotonation, pyridine-functionalized NHC ligands
Abstract: N-heterocyclic carbenes are extremely versatile ligands in homogeneous catalysis and coordination chemistry. A concurrent focus in this field is the construction of functionalized N-heterocyclic carbenes containing classical donor groups. The interest stems from the fact that multidentate ligand scaffolds can be finely constructed to fulfill specific purposes, such as providing extra-stability for metal complexes, possessing hemilability for effective generation of vacant coordination site, and allowing fine tuning of electronic and steric effects for inducing chemo-, stereo-, and enantioselectivities in catalytic reactions. There are numerous works on such multidentate ligands reported in the literature, in particular, those containing phosphorus, oxygen, and nitrogen functionalities. In this review, we will summarize the current development on functionalized N-heterocyclic carbenes in combination with classical donors of group 15 and 16 elements, illustrating typical preparations of the ligand precursors and their transition metal complexes. The coordination chemistry as well as catalytic applications of these ligands will be presented.
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Cite this article as:
Lee Man Hon, Lee Chun-Chin and Cheng Pi-Yun, Recent Development of Functionalized N-heterocyclic Carbene Ligands:Coordination Chemistry and Catalytic Applications, Current Organic Chemistry 2007; 11 (17) . https://dx.doi.org/10.2174/138527207782418681
DOI https://dx.doi.org/10.2174/138527207782418681 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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