Title:Ionic Liquids: A New Strategy in Pharmaceutical Synthesis
VOLUME: 9 ISSUE: 2
Author(s):Tomasz Siodmiak, Michal Piotr Marszall and Anna Proszowska
Affiliation:Collegium Medicum im. L. Rydygiera, ul. M. Sklodowskiej-Curie 9, 85-094 Bydgoszcz, Poland.
Keywords:Active pharmaceutical ingredient, biocatalytic reaction, green chemistry, ionic liquid, RTILs, antiparasitic drugs, DMAP, NSAIDs, CPPO, BNCT, Prvadoline
Abstract:The industrial synthesis of pharmaceutical compounds often involves the use of organic solvents. Unfortunately, these reaction
media are responsible for organic contaminations in the final product. In recent years, ionic liquids (ILs) have become the “green alternatives”
of volatile organic solvents. Thus, the application of ILs instead of conventional reagents offer a new opportunity to solve problems
of environmentally harmful solvents. This mini-review discusses a new application of ILs in laboratory-scale pharmaceutical synthesis.
