Abstract
Beneficial rapid onset effects of omega-3 fatty acids from fish oil on host defense compensatory fit into the comprehensive pathophysiology of critical illness. Because of balanced pro- and anti-inflammatory effects on a variety of host defense subsystems even septic patients had earlier recovery and improved survival. This review focuses in a compressed view on the beneficial aspects of omega-3 fatty acid supplementation on diverse organ functions, host defense and on balanced pro - and anti-inflammatory effects. Clinical impact of fish oil based pharmaconutrition during critical inflammation processes and immune response in humans is thoroughly discussed.
Keywords: Nutrition, fish oil, immunity, acute phase response, omega-3 fatty acids, intensive care medicine, critical illness, lung injury
Mini-Reviews in Medicinal Chemistry
Title: Pharmaconutrition with Omega-3 Fatty Acids: Status Quo and Further Perspectives
Volume: 8 Issue: 2
Author(s): Axel R. Heller
Affiliation:
Keywords: Nutrition, fish oil, immunity, acute phase response, omega-3 fatty acids, intensive care medicine, critical illness, lung injury
Abstract: Beneficial rapid onset effects of omega-3 fatty acids from fish oil on host defense compensatory fit into the comprehensive pathophysiology of critical illness. Because of balanced pro- and anti-inflammatory effects on a variety of host defense subsystems even septic patients had earlier recovery and improved survival. This review focuses in a compressed view on the beneficial aspects of omega-3 fatty acid supplementation on diverse organ functions, host defense and on balanced pro - and anti-inflammatory effects. Clinical impact of fish oil based pharmaconutrition during critical inflammation processes and immune response in humans is thoroughly discussed.
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Cite this article as:
Heller R. Axel, Pharmaconutrition with Omega-3 Fatty Acids: Status Quo and Further Perspectives, Mini-Reviews in Medicinal Chemistry 2008; 8 (2) . https://dx.doi.org/10.2174/138955708783498122
DOI https://dx.doi.org/10.2174/138955708783498122 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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