Clinical trials demonstrated that statin therapy is associated with a significant reduction in cardiovascular morbidity
and mortality when used for either primary or secondary prevention of cardiovascular events. Several studies have
shown that statins, having an important effect in the prevention of acute coronary syndromes, are also able to prevent
heart failure (HF) in patients with coronary artery disease. This review summarizes the experimental and clinical evidence
regarding the role of statins in the management of HF.
Keywords: Statins, heart failure.
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