Historically, patients with advanced structural heart disease have required major surgery to correct the defect. This includes, for example, patients with atrial septal defect, aortic valve disease and mitral valve ....
This book provides a comprehensive overview of current knowledge about research in oral infections and their association with cardiovascular diseases. Several epidemiological, clinical and other scientific aspects are covered in ....
Cardiac Resynchronization Therapy: An Established Pacing Therapy for Heart Failure and Mechanical Dyssynchrony
In recent decades, the prevalence of heart failure has steadily increased and can be considered a contemporary cardiovascular epidemic. Therefore, treatment of heart failure is a primary focus of cardiovascular ....
This comprehensive ebook covers all the aspects of ADME/PK modeling including solubility, absorption, formulation, metabolic stability, drug-drug interaction potential and a special delivery tool of drug candidates. The book provides ....
The Pharmaceutical Scientist Guide to Solution Kinetic Models Mathematical Description and Applications
Thermodynamics and kinetics (i.e., chemical interactions) are extremely important concepts for pharmaceutical scientists to understand since the “drug selection process”, that is, the process used by pharmaceutical companies to discover ....
Micro RNAs (miRNAs) are known to play an important role in gene expression regulation. Owing to their ever-increasing implications in the control of various biological and pathological processes, miRNAs have ....
The simple assessment of atherosclerotic risk factors is not an accurate tool to predict the risk of cardiovascular disease (CVD) in adults without past history of atherosclerotic disease. Preclinical atherosclerotic ....
Congenital heart diseases are the most common neonatal malformations, ranging from 8 to 15/1000 live births in various communities. Improvement of knowledge in the genetic and etio-pathogenic aspects of these ....
Degenerative Aortic Valve Disease, its Mechanism on Progression, its Effect on the Left Ventricle and the Postoperative Results
"Degenerative aortic valve disease is the most prominent cardiac valve disease in Western societies. This volume describes some of the more important issues and problems for this condition: its progressive ....