Abstract
Immune system plays an important role in control of tumor progression. Effective antitumor immune response depends on close interaction of several elements of immune system. They include antigen-presenting cells, different subsets of T cells, B cells and NK cells. However, tumor cells developed a number of mechanisms to escape recognition and elimination by immune system. In this review we will discuss these mechanisms and address possible approaches to correct them.
Keywords: Immune, tumor cells, antigen-presenting cells
Current Drug Targets
Title: Tumor Escape from Immune Response: Mechanisms and Targets of Activity
Volume: 4 Issue: 7
Author(s): Dmitry Gabrilovich and Vladimir Pisarev
Affiliation:
Keywords: Immune, tumor cells, antigen-presenting cells
Abstract: Immune system plays an important role in control of tumor progression. Effective antitumor immune response depends on close interaction of several elements of immune system. They include antigen-presenting cells, different subsets of T cells, B cells and NK cells. However, tumor cells developed a number of mechanisms to escape recognition and elimination by immune system. In this review we will discuss these mechanisms and address possible approaches to correct them.
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Cite this article as:
Gabrilovich Dmitry and Pisarev Vladimir, Tumor Escape from Immune Response: Mechanisms and Targets of Activity, Current Drug Targets 2003; 4 (7) . https://dx.doi.org/10.2174/1389450033490849
DOI https://dx.doi.org/10.2174/1389450033490849 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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