Background: In December 2019, a large number of patients with a novel coronavirus
were identified in Wuhan, China. The novel coronavirus (COVID-19) is highly contagious and increasing
the rate of mortality day by day. The World Health Organization declared COVID-19 as a
worldwide pandemic on March 11, 2020. Early diagnosis of SARS-CoV-2 can restrict the
Objective: We aim to study the currently available diagnostic methods for COVID-19.
Methods: World Health Organisation portal, Centre for Disease Control and Prevention portal, Indian
Council of Medical Research portal, Chinese Centre for Disease Control and Prevention portal,
Science Direct, Google Scholar, Research Gate, etc. were searched for obtaining data.
Results: Rapid diagnosis and prompt treatment can reduce the number of prospective cases. The diagnostic
strategy encompasses the screening of the virus with nucleic acid amplification test
(NAAT) such as real-time reverse-transcription polymerase chain reaction (RT-PCR) assays. Serological
testing is a diagnostic procedure used for identifying the presence of immune responses. Radiological
findings in individuals with COVID-19 are characterised by multiple areas of consolidation
in the chest. Rapid antigen tests are in-vitro diagnostics that have been designed to give results
within 10-20 min.
Conclusion: Rapid, simple, and safe diagnosis of COVID-19 has a great impact on deciding clinical
and epidemiological factors. RT-PCR results often require 5 to 6 hours. Diagnosis by serological
testing is not suitable but important epidemiologically. At present, the best radiological strategy
remains undefined. Rapid antigen tests have limitations on sensitivity.