Background: Coronavirus disease (COVID-19) is spreading rapidly at an unprecedented
scale across continents and has emerged as the single biggest risk the world has faced in modern times.
Some scientists are comparing it to Spanish flu that created havoc around a century ago. The fear of
death by COVID-19 looms large in the world today. The disease has reached devastating proportions
since its first reports in December 2019. Doctors are having a difficult time dealing with this challenge
and the microbiologists are having sleepless nights to bring about an effective vaccine for this disease.
Methods: A number of research and review articles have been exhaustively reviewed. The collected data
has been meticulously analyzed and documented.
Conclusion: This paper reviews the different types of coronaviruses, the structure of SARS-CoV-2 responsible
for COVID-19, its transmission, and virulence. Further, the article discusses the diagnosis,
signs and symptoms like fever, breathlessness, cough, potential loss of taste or smell, sneezing, runny
nose, fatigue, headache, sore throat and different treatment approaches including drug repurposing being
tried by doctors around the globe that may come handy in the management of disease symptoms. The
article describes the use of remdesivir, ribavarin, lopinavir, favipiravir, hydoxychloroquine, chloroquine,
and tocilizumab among others in treating COVID-19.