Abstract
Medicinal plants are known for their many advantages, including the ability to treat diseases such as cancer. Nigella sativa and its active constituent thymoquinone (TQ) have long been used in traditional medicine for treating various conditions related to the respiratory and gastrointestinal systems as well as breast, colorectal, gastric, hepatic, pancreatic cancers and leukemia. TQ has been documented to possess chemo-preventive and chemotherapeutic antitumor effects. Studies reported that TQ inhibits the growth of cancer cells in animal models and culture tumors. This review summarizes the in vitro and in vivo possible mechanisms of TQ anticancer effect.
Keywords: Anticancer, pathways, thymoquinone.
Current Drug Discovery Technologies
Title:Thymoquinone Anticancer Discovery: Possible Mechanisms
Volume: 12 Issue: 2
Author(s): Ali H. El-Far
Affiliation:
Keywords: Anticancer, pathways, thymoquinone.
Abstract: Medicinal plants are known for their many advantages, including the ability to treat diseases such as cancer. Nigella sativa and its active constituent thymoquinone (TQ) have long been used in traditional medicine for treating various conditions related to the respiratory and gastrointestinal systems as well as breast, colorectal, gastric, hepatic, pancreatic cancers and leukemia. TQ has been documented to possess chemo-preventive and chemotherapeutic antitumor effects. Studies reported that TQ inhibits the growth of cancer cells in animal models and culture tumors. This review summarizes the in vitro and in vivo possible mechanisms of TQ anticancer effect.
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Cite this article as:
El-Far H. Ali, Thymoquinone Anticancer Discovery: Possible Mechanisms, Current Drug Discovery Technologies 2015; 12 (2) . https://dx.doi.org/10.2174/1570163812666150716111821
DOI https://dx.doi.org/10.2174/1570163812666150716111821 |
Print ISSN 1570-1638 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6220 |
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