Can Topiramate Induce Pruritus? A Case Report and Review of Literature

Author(s): Maria S. Signorelli, Maria Cinconze, Maria R. Nasca, Monica Marino, Giovanni Martinotti, Massimo Di Giannantonio, Eugenio Aguglia

Journal Name: CNS & Neurological Disorders - Drug Targets
Formerly Current Drug Targets - CNS & Neurological Disorders

Volume 14 , Issue 3 , 2015

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A 41-year-old woman with Major Depressive Disorder-Recurrent was treated with topiramate at 150 mg/day. After this administration, she developed intense pruritus and skin lesions due to scratching. Consequently, she was weaned off topiramate and the lesions regressed. Pruritus and cutaneous lesions are extremely rare side effects of topiramate, so we report an interesting case of skin reaction to this drug.

Keywords: Depression, mood stabilizers, pruritus, side effects, skin disorders, topiramate.

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Article Details

Year: 2015
Published on: 25 February, 2015
Page: [309 - 312]
Pages: 4
DOI: 10.2174/1871527314666150225123827
Price: $65

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