Title:Current and Potential Treatments for Cervical Cancer
VOLUME: 13 ISSUE: 2
Author(s):Grace P.C. Yee, Paul de Souza and Levon M. Khachigian
Affiliation:Centre for Vascular Research, University of New South Wales, Sydney, NSW 2052, Australia
Keywords:Cervical cancer, side-effects, targeted, therapy.
Abstract:Cervical cancer is the third most common carcinoma in women worldwide. Despite increasing efforts to
improve therapy in this disease, a significant proportion of women still die, mostly from recurrent or chemoresistant
disease. This review discusses current treatments for early cervical cancer, advanced disease, and recurrent cervical
cancer, and covers concurrent chemoradiation, neoadjuvant chemotherapy before surgery and radiation, single agent
treatment, combination treatment, platinum-based and non-platinum based therapy. We also discuss promising therapeutic
strategies for cervical cancer including targeted therapy, cell-based therapy, combined siRNA and chemotherapy, and
immunotherapy.