This present review submitted high-performance liquid chromatography (HPLC) methods for determining the
presence of meloxicam used in clinical treatment within various fields of application, including biological samples and
pharmaceutical formulations, between 1990 and 2011.
Meloxicam is a cyclooxygenase-2 selective nonsteroidal anti-inflammatory drug (NSAIDs), which is the group most often
used in human health care. We compared the methods from the standpoint of sensitivity. HPLC methods with MS/MS detection
have become the method of choice in bioanalytical applications.
Keywords: Meloxicam, HPLC, Review, Pharmaceutical preparations, Biological samples, cyclooxygenase, NSAIDs, sensitivity, hemorrhagia, physiological, methylthiazole system
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