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Current Medical Imaging


ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

Case Report

Characteristic Imaging Features of Merkel Cell Carcinoma: A Case Report

Author(s): Hyun Jin Kim, Kyu-Chong Lee*, Chang Ho Kang, Kyung-Sik Ahn and Chul Hwan Kim

Volume 17 , Issue 4 , 2021

Published on: 23 October, 2020

Page: [562 - 566] Pages: 5

DOI: 10.2174/1573405616666201023142724

Price: $65


Background: Merkel cell carcinoma (MCC) is a rare primary cutaneous tumor. The standardized imaging guidelines for the diagnosis of MCC have not been established. We report the multimodality imaging features of MCC, including CT, MRI, and ultrasound with grayscale and color Doppler mode as well as the elastography and even a histopathologic confirmation.

Case Report: We report the case of a 76-year old male patient with MCC on the elbow that was treated by excision. On MRI, prominent T2 low signal voiding was noted with branching or chaotic pattern and marked, branching, or chaotic vascularity was also seen on color doppler ultrasound. Those findings corresponded to histology that showed increased vascularity in stromal tissues of the tumor and in between the tumor cells.

Conclusion: A mass in the dermal and subcutaneous layer with marked and branching or chaotic vascularity may be the unique characteristic that may contribute to early diagnosis of MCC.

Keywords: Merkel cell carcinoma (MCC), magnetic resonance imaging, ultrasound, color doppler mode, branching or chaotic vascularity, elastography.

Graphical Abstract
Tirumani SH, Shinagare AB, Sakellis C, et al. Merkel cell carcinoma: a primer for the radiologist. AJR Am J Roentgenol 2013; 200(6): 1186-96.
[PMID: 23701052]
Enzenhofer E, Ubl P, Czerny C, Erovic BM. Imaging in patients with merkel cell carcinoma. J Skin Cancer 2013; 2013973123
[] [PMID: 23476783]
Peloschek P, Novotny C, Mueller-Mang C, et al. Diagnostic imaging in Merkel cell carcinoma: lessons to learn from 16 cases with correlation of sonography, CT, MRI and PET. Eur J Radiol 2010; 73(2): 317-23.
[] [PMID: 19108971]
Nguyen BD, McCullough AE. Imaging of Merkel cell carcinoma. Radiographics 2002; 22(2): 367-76.
[] [PMID: 11896226]
Wortsman X, Gregor BE. Dermatologic Ultrasound with Clinical and Histologic Correlations. Springer Science Business Media New York 2013; pp. 249-80.
Catalano O, Alfageme Roldán F, Scotto di Santolo M, Solivetti FM, Wortsman X. Color Doppler Sonography of Merkel Cell Carcinoma. J Ultrasound Med 2018; 37(1): 285-92.
[] [PMID: 28726278]
Hernández-Aragüés I, Vázquez-Osorio I, Alfageme F, et al. Skin ultrasound features of Merkel cell carcinoma. J Eur Acad Dermatol Venereol 2017; 31(7): e315-8.
[] [PMID: 28045198]
Kim SH, Han MH, Park SW, Chang KH. Radiologic-pathologic correlation of unusual lingual masses: Part II: benign and malignant tumors. Korean J Radiol 2001; 2(1): 42-51.
[] [PMID: 11752968]

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