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Endocrine, Metabolic & Immune Disorders - Drug Targets


ISSN (Print): 1871-5303
ISSN (Online): 2212-3873

Review Article

Benefits of Olive Oil Phenolic Compounds in Disease Prevention

Author(s): Olga Garcia-Martinez, Concepcion Ruiz*, Alvaro Gutierrez-Ibanez, Rebeca Illescas-Montes and Lucia Melguizo-Rodriguez

Volume 18, Issue 4, 2018

Page: [333 - 340] Pages: 8

DOI: 10.2174/1871530318666180213113211

Price: $65


Background and Objective: The preventive effects of olive oil against different diseases have been attributed to its high phenolic compound content. The objective of this study was to examine available scientific evidence on the beneficial effects against chronic diseases of olive oil phenolic compounds.

Method: This article examines recently published data on olive oil phenolic compounds and their potential benefits in the prevention of cardiovascular disease, cancer, neurodegenerative disease, and osteoporosis.

Results: The antioxidant, anti-proliferative, pro-apoptotic, and anti-inflammatory activities of olive oil phenolic compounds have preventive effects against heart disease and cancer. These compounds also exert neuroprotective and neuromodulator effects against neurodegenerative disease, inhibiting the development of amyloid plaques. Finally, they are known to protect against osteoporosis, favoring bone regeneration.

Conclusion: Dietary intake of olive oil can be recommended by healthcare professionals as an important source of phenolic compounds that play a role in the prevention of chronic disease and the consequent improvement in quality of life.

Keywords: Olive oil, phenolic compounds, cardiovascular disease, cancer, neurodegenerative disease, osteoporosis.

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