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Protein & Peptide Letters


ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

Intein-Mediated, In Vitro and In Vivo Protein Modifications with Small Molecules

Author(s): Lay P. Tan and Shao Q. Yao

Volume 12, Issue 8, 2005

Page: [769 - 775] Pages: 7

DOI: 10.2174/0929866054864193

Price: $65


We review intein-mediated approaches for the site-specific modifications of proteins and highlight their applications in (1) the site-specific in vitro and in vivo biotinylation of proteins for protein arrays and (2) the site-specific in vivo labeling of proteins in living cells.

Keywords: intein, biotinylation, native chemical ligation, protein arrays, bioimaging, site-specific

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