Abstract
Turmeric (Curcuma longa L., Zingiberaceae family) is a well known Chinese herbal medicine. It possesses diverse pharmacologic effects including antioxidant, anti-inflammatory, antiproliferative and antiangiogenic activities. The main bioactive constituents of C. longa include sesquiterpenes, which are responsible for its aroma, and curcuminoids, which contribute to its bright yellow color. Both sesquiterpenes and curcuminoids exhibit great potential as therapeutic agents for various diseases including colon cancer, pancreatic cancer, diabetes and Alzheimer's disease. Particularly, curcumin, one of the major curcuminoids of turmeric, has been proved to be effective in cancer treatment and prevention by recent phase I clinical trials. In order to ensure the efficacy and safety of turmeric in clinical applications, sensitive and accurate analytical methods are of significance for the comprehensive quality control of C. longa. This review summarizes recent progress in the chemical analysis of sesquiterpenes and curcuminoids in turmeric.
Keywords: Curcuma longa L, Sesquiterpenes, Curcuminoids, Chemical analysis, Quality control, Chinese herbal medicine
Current Pharmaceutical Analysis
Title: Chemical Analysis of the Chinese Herbal Medicine Turmeric (Curcuma longa L.)
Volume: 6 Issue: 4
Author(s): Rui Li, Cheng Xiang, Xing Zhang, De-An Guo and Min Ye
Affiliation:
Keywords: Curcuma longa L, Sesquiterpenes, Curcuminoids, Chemical analysis, Quality control, Chinese herbal medicine
Abstract: Turmeric (Curcuma longa L., Zingiberaceae family) is a well known Chinese herbal medicine. It possesses diverse pharmacologic effects including antioxidant, anti-inflammatory, antiproliferative and antiangiogenic activities. The main bioactive constituents of C. longa include sesquiterpenes, which are responsible for its aroma, and curcuminoids, which contribute to its bright yellow color. Both sesquiterpenes and curcuminoids exhibit great potential as therapeutic agents for various diseases including colon cancer, pancreatic cancer, diabetes and Alzheimer's disease. Particularly, curcumin, one of the major curcuminoids of turmeric, has been proved to be effective in cancer treatment and prevention by recent phase I clinical trials. In order to ensure the efficacy and safety of turmeric in clinical applications, sensitive and accurate analytical methods are of significance for the comprehensive quality control of C. longa. This review summarizes recent progress in the chemical analysis of sesquiterpenes and curcuminoids in turmeric.
Export Options
About this article
Cite this article as:
Li Rui, Xiang Cheng, Zhang Xing, Guo De-An and Ye Min, Chemical Analysis of the Chinese Herbal Medicine Turmeric (Curcuma longa L.), Current Pharmaceutical Analysis 2010; 6 (4) . https://dx.doi.org/10.2174/157341210793292356
DOI https://dx.doi.org/10.2174/157341210793292356 |
Print ISSN 1573-4129 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-676X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Ascorbic Acid and Gene Expression: Another Example of Regulation of Gene Expression by Small Molecules?
Current Genomics Epigallocatechin-3-gallate(EGCG): Mechanisms and the Combined Applications
Combinatorial Chemistry & High Throughput Screening Real-World Clinical Effectiveness and Tolerability of Hydroxychloroquine 400 Mg in Uncontrolled Type 2 Diabetes Subjects who are not Willing to Initiate Insulin Therapy (HYQ-Real-World Study)
Current Diabetes Reviews Insulin Resistance and Hypertension
Current Hypertension Reviews Natural AMPK Activators: An Alternative Approach for the Treatment and Management of Metabolic Syndrome
Current Medicinal Chemistry Editorial (Thematic Issue: New Horizon in the Treatment of Hypertension - Role for Ca Channel Blockers - Why do Ca Channel Blockers be Focused on?)
Current Hypertension Reviews Proliferative Retinopathies: Animal Models and Therapeutic Opportunities
Current Neurovascular Research The Problem of Atrial Fibrillation in Patients with Chronic Kidney Disease
Current Vascular Pharmacology Therapeutic Potential of Resveratrol in Diabetic Nephropathy According to Molecular Signaling
Current Molecular Pharmacology Patent Annotations
Recent Patents on Cardiovascular Drug Discovery Pyrazolines: A Biological Review
Mini-Reviews in Medicinal Chemistry The Role of STAT 3 in Tissue Fibrosis
Current Chemical Biology Influence of Diabetes on the Pharmacokinetic Behavior of Natural Polyphenols
Current Drug Metabolism Changes in Serum Nampt Levels and Its Significances in Diabetic Nephropathy Patients-The Potential Role of Nampt in T2DM with Diabetic Nephropathy
Endocrine, Metabolic & Immune Disorders - Drug Targets T-type Ca Channel Blockers in Patients with Chronic Kidney Disease in Clinical Practice
Current Hypertension Reviews Advent and Maturation of Regenerative Medicine
Current Stem Cell Research & Therapy Usefulness of Home Blood Pressure in the Diagnosis and Control of Hypertension in Primary Care
Current Hypertension Reviews Adverse Drug Reactions Amongst Adult Patients Admitted in Lagos State University Teaching Hospital Lagos, Nigeria
Current Drug Safety Curcumin: A Potential Neuroprotective Agent in Parkinson's Disease
Current Pharmaceutical Design Risk Factors Identification and Prediction of Anemia among Women in Bangladesh using Machine Learning Techniques
Current Women`s Health Reviews