Abstract
Fungi are relatively rare causes of pulmonary infection and outside areas of endemic mycoses, infections are mainly opportunist caused by Pneumocystis and Aspergillus species. Invasive aspergillosis may be an undiagnosed problem in critically ill patients particularly those with end stage of lung and liver failure. The attributable mortality and impact of antifungal treatment are unknown. A raised index of clinical suspicion should lead to antigen testing on respiratory specimens from selected critical care patients to aid in earlier diagnosis. The high negative predictive value can be used to exclude diagnosis.
Keywords: Aspergillus, ICU, Pneumocystis, pulmonary infection, Pneumocystis, Aspergillus, endemic mycoses, chronic disease, allergic bronchopulmonary aspergillosis
Current Respiratory Medicine Reviews
Title:Diagnosis and Treatment of Pulmonary Fungal Infections in Critically Ill Patients
Volume: 8 Issue: 3
Author(s): Rosemary A. Barnes
Affiliation:
Keywords: Aspergillus, ICU, Pneumocystis, pulmonary infection, Pneumocystis, Aspergillus, endemic mycoses, chronic disease, allergic bronchopulmonary aspergillosis
Abstract: Fungi are relatively rare causes of pulmonary infection and outside areas of endemic mycoses, infections are mainly opportunist caused by Pneumocystis and Aspergillus species. Invasive aspergillosis may be an undiagnosed problem in critically ill patients particularly those with end stage of lung and liver failure. The attributable mortality and impact of antifungal treatment are unknown. A raised index of clinical suspicion should lead to antigen testing on respiratory specimens from selected critical care patients to aid in earlier diagnosis. The high negative predictive value can be used to exclude diagnosis.
Export Options
About this article
Cite this article as:
A. Barnes Rosemary, Diagnosis and Treatment of Pulmonary Fungal Infections in Critically Ill Patients, Current Respiratory Medicine Reviews 2012; 8 (3) . https://dx.doi.org/10.2174/157339812800493304
DOI https://dx.doi.org/10.2174/157339812800493304 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Chronic Eosinophilic Leukemia, Not Otherwise Specified (CEL, NOS)
Current Cancer Therapy Reviews Assessment of Thyroid Disorders and Autoimmunity in Patients with Rheumatic Diseases
Endocrine, Metabolic & Immune Disorders - Drug Targets KRAB-Zinc Finger Proteins: A Repressor Family Displaying Multiple Biological Functions
Current Genomics 3D QSAR of Aminophenyl Benzamide Derivatives as Histone Deacetylase Inhibitors
Medicinal Chemistry In-silico Evidences of Regulatory Roles of WT1 Transcription Factor Binding Sites on the Intervening Sequences of the Human Bcl-2 Gene
Current Bioinformatics CAR-NK Cells for Cancer Therapy: Molecular Redesign of the Innate Antineoplastic Response
Current Gene Therapy Current Targets for Anticancer Drug Discovery
Current Drug Targets Current Treatment Concepts of Philadelphia-Negative MPN
Current Cancer Drug Targets MicroRNAs in Leukemias: Emerging Diagnostic Tools and Therapeutic Targets
Current Drug Targets On the Power of Additional and Complex Chromosomal Aberrations in CML
Current Genomics Novel Therapeutic Approaches Targeting Vascular Endothelial Growth Factor and its Receptors in Haematological Malignancies
Current Cancer Drug Targets Gene Expression-Based Pharmacodynamic Biomarkers: The Beginning of a New Era in Biomarker-Driven Anti-Tumor Drug Development
Current Molecular Medicine Quality of Life in Patients with β-thalassemia Major: Short-term and Long-term Effects After Haematopoietic Stem Cell Transplantation
Current Stem Cell Research & Therapy Bench to Bedside Targeting of FLT3 in Acute Leukemia
Current Drug Targets Bronchiolitis Obliterans Following Lung Transplantation and Stem Cell Transplantation in Pediatric Patients
Current Pediatric Reviews Diagnostic Methods in the Detection of Prostate Cancer: Prospective Observational Study
Current Medical Imaging The Use of Therapeutic Peptides to Target and to Kill Cancer Cells
Current Medicinal Chemistry Therapeutic Perspectives for cN-II in Cancer.
Current Medicinal Chemistry Molecular Monitoring of Immune Reconstitution After Haploidentical Stem Cell Transplantation
Current Stem Cell Research & Therapy Current Therapeutic Approaches in Inflammatory Bowel Disease
Current Pharmaceutical Design