Design and Synthesis of Metal-Free Artificial Ribonucleases

Author(s): Ludmila S. Koroleva, Inna Yu. Serpokrylova, Valentin V. Vlassov, Vladimir N. Silnikov

Journal Name: Protein & Peptide Letters

Volume 14 , Issue 2 , 2007

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Abstract:

The present review is aimed at giving a general overview of our results in the field of designing and synthesizing simple peptide-like molecules that mimic structural and functional aspects of natural ribonucleases, as well as designing oligonucleotide-based artificial ribonucleases.

Keywords: Artificial ribonucleases, RNases mimics, oligonucleotide conjugates

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Article Details

VOLUME: 14
ISSUE: 2
Year: 2007
Page: [151 - 163]
Pages: 13
DOI: 10.2174/092986607779816177
Price: $65

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