Search Result "designed multiple ligands"


Review Article

Changing Paradigm from one Target one Ligand Towards Multi-target Directed Ligand Design for Key Drug Targets of Alzheimer Disease: An Important Role of In Silico Methods in Multi-target Directed Ligands Design

Journal: Current Neuropharmacology
Volume: 16 Issue: 6 Year: 2018 Page: 726-739
Author(s): Akhil Kumar,Ashish Tiwari,Ashok Sharma

Research Article

Scoring Ligand Efficiency: Potency, Ligand Efficiency and Product Ligand Efficiency within Big Data Landscape

Journal: Letters in Drug Design & Discovery
Volume: 16 Issue: 1 Year: 2019 Page: 1258-1263
Author(s): Jaroslaw Polanski,Anna Pedrys,Roksana Duszkiewicz,Johann Gasteiger

Metallo-Organic G-Quadruplex Ligands in Anticancer Drug Design

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 10 Issue: 8 Year: 2010 Page: 726-736
Author(s): Y.-L. Jiang, Z.-P. Liu

On the Paradigm Shift Towards Multitarget Selective Drug Design

Journal: Current Computer-Aided Drug Design
Volume: 4 Issue: 2 Year: 2008 Page: 76-90
Author(s): Nigus Dessalew, Workalemahu Mikre

Combining Ligand- and Structure-Based Methods in Drug Design Projects

Journal: Current Computer-Aided Drug Design
Volume: 4 Issue: 3 Year: 2008 Page: 250-258
Author(s): Olivier Sperandio, Maria A. Miteva, Bruno O. Villoutreix

Drug Design of GPCR Ligands Using Physicogenetics and Chemogenomics - Principles and Case Studies

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 1882-1901
Author(s): Thomas M. Frimurer, Thomas Hogberg

Specific Noncovalent Interactions at Protein-Ligand Interface: Implications for Rational Drug Design

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 2 Year: 2012 Page: 226-238
Author(s): P. Zhou, J. Huang, F. Tian

PPAR Ligands for Metabolic Disorders

Journal: Current Topics in Medicinal Chemistry
Volume: 3 Issue: 1 Year: 2003 Page: 1649-1661
Author(s): Garret J. Etgen, Nathan Mantlo

Recent Advances in Ligand-Based Drug Design: Relevance and Utility of the Conformationally Sampled Pharmacophore Approach

Journal: Current Computer-Aided Drug Design
Volume: 7 Issue: 1 Year: 2011 Page: 10-22
Author(s): Chayan Acharya, Andrew Coop, James E. Polli, Alexander D. MacKerell

Ligand-Based Peptide Design and Combinatorial Peptide Libraries to Target G Protein-Coupled Receptors

Journal: Current Pharmaceutical Design
Volume: 16 Issue: 2 Year: 2010 Page: 3071-3088
Author(s): Christian W. Gruber, Markus Muttenthaler, Michael Freissmuth

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