Search Result "Isostere"


Recent Progress in the Medicinal Chemistry of γ-Secretase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 17-33
Author(s): Richard E. Olson, Charles F. Albright

Solution Phase Synthesis of a 3,5,7-Substituted Indolin-2-one Library as Potential CDK2 Inhibitor Isosteres

Journal: Letters in Drug Design & Discovery
Volume: 5 Issue: 1 Year: 2008 Page: 43-47
Author(s): Dmytro O. Tymoshenko, Brian T. Gregg, Matthew J. Hirsch, Jennifer L. Butcher

Design and Synthesis of Novel Diaryl Heterocyclic Derivatives as Selective Cyclooxygenase-2

Journal: Letters in Drug Design & Discovery
Volume: 5 Issue: 2 Year: 2008 Page: 127-133
Author(s): S. X. Li, X. D. Deng, F. L. Jiang, Y. J. Zhao, W. S. Xiao, X. Z. Kuang, X. M. Sun

Design, Synthesis and Anticancer Activity Against the MCF-7 Cell Line of Benzo-Fused 1,4-Dihetero Seven- and Six-Membered Tethered Pyrimidines and Purines

Journal: Current Medicinal Chemistry
Volume: 15 Issue: 2 Year: 2008 Page: 2614-2631
Author(s): Maria C. Nunez, Monica Diaz-Gavilan, Ana Conejo-Garcia, Olga Cruz-Lopez, Miguel A. Gallo, Antonio Espinosa, Joaquin M. Campos

Carbonic Anhydrases An Overview

Journal: Current Pharmaceutical Design
Volume: 14 Issue: 7 Year: 2008 Page: 603-614
Author(s): Claudiu T. Supuran

Recent Advances on Isoniazide Derivatives

Journal: Anti-Infective Agents in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2008 Page: 12-31
Author(s): Jarmila Vinsova, Ales Imramovsky, Josef Jampilek, Juana Ferriz Monreal, Martin Dolezal

The Role of Structure Activity Relationship Studies in the Search for New GABA Uptake Inhibitors

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1214-1223
Author(s): Katarzyna Kulig, Marta Szwaczkiewicz

TMSCl-NaI-MeCN Reagent Mediated Simple Two-Step Synthesis of Phenolic Benzosultams

Journal: Letters in Organic Chemistry
Volume: 5 Issue: 6 Year: 2008 Page: 461-463
Author(s): Rui Wang, Fang Fang, Long-Qian Tang, Zhao-Peng Liu

Phosphorylation-Specific Prolyl Isomerase Pin1 as a new Diagnostic and Therapeutic Target for Cancer

Journal: Current Cancer Drug Targets
Volume: 8 Issue: 3 Year: 2008 Page: 223-229
Author(s): Greg Finn, Kun Ping Lu

Organophosphorus Compounds: Intervention in Mechanisms of Signal Transduction Relevant to Proliferative, Immunological and Circulatory Disorders

Journal: Current Medicinal Chemistry
Volume: 15 Issue: 2 Year: 2008 Page: 2230-2257
Author(s): Nick J. Wardle, S. W. Annie Bligh, Harry R. Hudson

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