Abstract
Heterocyclic compounds hold an important place in the realm of medicinal
chemistry due to their vast pharmacological and therapeutic significance. Worldwide,
cancer is the leading cause of death, and developing an appropriate treatment for the
management of cancer is a challenge. Efforts are being made continuously to search for
a suitable medicinal agent to treat cancer. Chromene (benzopyran) is an important
scaffold and is also considered a privileged pharmacophore. This scaffold also appears
as an important structural component in various natural products. The various
substituted and fused chromenes display propitious activity against various types of
cancer. This chapter highlights the latest advancements from the year 2015 to date on
chromene-based molecules that have anticancer activities. A subpart briefing natural
chromenes containing anticancer potential is also incorporated.
Keywords: Cancer, Cell line, Chromene, Cytotoxicity, Heterocycle, IC50.
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