摘要
_在过去十年中,炎症性肠病(IBD)的治疗策略和治疗方案发生了很大变化。 除了治疗方案的这种转变,还有机会根据患者的个人情况和偏好个性化治疗决策。 IBD治疗最重要的方面之一是治疗相关风险,并且有机会通过优化个体患者的药物安全性来个性化治疗。 在这篇综述中,我们讨论IBD治疗的潜在风险,缓解这些风险的机会以及在临床实践中使用这些药物时需要考虑的个性化方法。
关键词: 克罗恩氏病,溃疡性结肠炎,风险,不良事件,炎症性肠病,感染。
Current Drug Targets
Title:Optimization of Drug Safety Profile in Inflammatory Bowel Disease Through a Personalized Approach
Volume: 19 Issue: 7
关键词: 克罗恩氏病,溃疡性结肠炎,风险,不良事件,炎症性肠病,感染。
摘要: Treatment strategies and treatment options have changed considerably over the past decade for Inflammatory Bowel Disease (IBD). Alongside this shift in therapeutic options has come an opportunity to personalize treatment decisions based on individual patient profiles and preferences. One of the most important aspects of therapy in IBD is treatment related risk, and an opportunity exists to personalize therapy through optimization of drug safety profiles in individual patients. In this review we discuss the potential risks of therapy in IBD, opportunities to mitigate those risks, and a personalized approach to consider when using these agents in clinical practice.
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Optimization of Drug Safety Profile in Inflammatory Bowel Disease Through a Personalized Approach, Current Drug Targets 2018; 19 (7) . https://dx.doi.org/10.2174/1389450118666170525114939
DOI https://dx.doi.org/10.2174/1389450118666170525114939 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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