Abstract
The prevalence of cancer in companion animals has increased in the recent decade, making this disease one of the major causes of deaths. As in human medicine, veterinary medicine faces the problem of cancer prevention as well as early diagnosis and effective therapy. Early diagnosis of cancer is crucial for the successful treatment of the disease and there is a need for biomarkers that could be used as a diagnostic tool, and to guide a targeted therapy or monitor a therapeutic response. Proteomic technologies that were introduced to human cancer research over a decade ago provide the opportunity to identify distinct protein patterns for cancer diagnosis and therapy monitoring. These also have potential to be utilised in veterinary medicine. The present paper summarises the current knowledge about proteomic studies on animal cancer biomarker research published to date.
Keywords: Cancer biomarker, IHC, proteomics, veterinary oncology.
Current Protein & Peptide Science
Title:Proteomics in the Search for Biomarkers of Animal Cancer
Volume: 15 Issue: 1
Author(s): Anna Kycko and Michal Reichert
Affiliation:
Keywords: Cancer biomarker, IHC, proteomics, veterinary oncology.
Abstract: The prevalence of cancer in companion animals has increased in the recent decade, making this disease one of the major causes of deaths. As in human medicine, veterinary medicine faces the problem of cancer prevention as well as early diagnosis and effective therapy. Early diagnosis of cancer is crucial for the successful treatment of the disease and there is a need for biomarkers that could be used as a diagnostic tool, and to guide a targeted therapy or monitor a therapeutic response. Proteomic technologies that were introduced to human cancer research over a decade ago provide the opportunity to identify distinct protein patterns for cancer diagnosis and therapy monitoring. These also have potential to be utilised in veterinary medicine. The present paper summarises the current knowledge about proteomic studies on animal cancer biomarker research published to date.
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Cite this article as:
Kycko Anna and Reichert Michal, Proteomics in the Search for Biomarkers of Animal Cancer, Current Protein & Peptide Science 2014; 15 (1) . https://dx.doi.org/10.2174/1389203715666140221110945
DOI https://dx.doi.org/10.2174/1389203715666140221110945 |
Print ISSN 1389-2037 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5550 |
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