Review Article

天然产物和营养食品对载脂蛋白B的调节:全面综述

卷 28, 期 7, 2021

发表于: 27 April, 2020

页: [1363 - 1406] 页: 44

弟呕挨: 10.2174/0929867327666200427092114

价格: $65

摘要

在发展中国家和工业化国家中,心血管疾病(CVD)都是最重要的死亡原因之一。从婴儿期到老年期都观察到与CVD相关的合并症。载脂蛋白B100(Apo B)是源自肝脏的所有主要致动脉粥样化颗粒的主要载脂蛋白和结构蛋白,包括极低密度脂蛋白(VLDL),中密度脂蛋白(IDL)和低密度脂蛋白(LDL)颗粒。已经提出,与LDL-C的测量相比,Apo B浓度的测量对于预测CVD风险是一种更好且更可靠的指标。营养食品和药用植物引起了极大的关注,因为它涉及非传染性疾病的治疗,尤其是CVD,糖尿病,高血压和非酒精性脂肪肝病(NAFLD)。先前已经研究了营养保健品和草药产品对CVD的影响,以及其某些危险因素(例如血脂异常)。然而,据我们所知,尚未研究这些天然产物,包括草药补品和功能性食品(例如,作为干料的水果和蔬菜,或其提取物)对Apo B的影响。因此,本文的主要目的是综述生物活性天然化合物对血浆Apo B浓度的影响。结论是,一般而言,药用植物和营养保健品可以用作补充药物,以安全,容易获得和廉价的方式降低血浆Apo B的水平,以尝试预防和治疗CVD。

关键词: 心血管疾病(CVD),植物化学物质,脂蛋白,血脂异常,载脂蛋白B,胆固醇。

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