Abstract
Background: The safety of zopiclone and other Z-drug use has been questioned in many regards. Past issues of side effects, tolerance, abuse, addition, and inappropriate uses have all deserved attention.
Objective: In this paper, the issue of zopiclone safety is again reviewed for information newly arising over the last decade. Method: Information databases were scanned for ‘zopiclone’, and all relevant literature was reviewed. Results: Zopiclone continues to be a very frequently consumed sedative-hypnotic. It is often found in the blood of those with drug abuse, self-harm, overdose, and road accidents. The drug is flourishing as a medication for the elderly, and numerous adverse consequences, including injury, have been associated with it. Zopiclone impairs driving ability, and methods to determine such impairment among active drivers are needed. Conclusion: We have previously suggested that zopiclone prescription and use should have the same concerns as those for benzodiazepine pharmacotherapy. There is evidently no need to change such a stance.Keywords: Zopiclone, risk, safety, side-effects, withdrawal, addiction.
Current Psychopharmacology
Title:Safety with Zopiclone Use: Contemporary Issues
Volume: 6
Author(s): Nevio Cimolai*
Affiliation:
- Department of Pathology and Laboratory Medicine, The University of British Columbia, Vancouver,Canada
Keywords: Zopiclone, risk, safety, side-effects, withdrawal, addiction.
Abstract: Background: The safety of zopiclone and other Z-drug use has been questioned in many regards. Past issues of side effects, tolerance, abuse, addition, and inappropriate uses have all deserved attention.
Objective: In this paper, the issue of zopiclone safety is again reviewed for information newly arising over the last decade. Method: Information databases were scanned for ‘zopiclone’, and all relevant literature was reviewed. Results: Zopiclone continues to be a very frequently consumed sedative-hypnotic. It is often found in the blood of those with drug abuse, self-harm, overdose, and road accidents. The drug is flourishing as a medication for the elderly, and numerous adverse consequences, including injury, have been associated with it. Zopiclone impairs driving ability, and methods to determine such impairment among active drivers are needed. Conclusion: We have previously suggested that zopiclone prescription and use should have the same concerns as those for benzodiazepine pharmacotherapy. There is evidently no need to change such a stance.Export Options
About this article
Cite this article as:
Cimolai Nevio*, Safety with Zopiclone Use: Contemporary Issues, Current Psychopharmacology 2017; 6 (1) . https://dx.doi.org/10.2174/2211556005666160822112843
DOI https://dx.doi.org/10.2174/2211556005666160822112843 |
Print ISSN 2211-5560 |
Publisher Name Bentham Science Publisher |
Online ISSN 2211-5579 |
Call for Papers in Thematic Issues
Breakthroughs in drug design, development and delivery system for the management of neuro-psychiatric disorders
Neuropsychiatric diseases are one of the main causes of disability, affecting millions of people. Various drugs are used for its treatment, although no effective therapy has been found yet. The blood brain barrier (BBB) significantly complicates drugs delivery to the target cells in the brain tissues. This proposal describes the ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
How do Glial Cells Contribute to Motor Control?
Current Pharmaceutical Design The Impact of Alexithymia on Anxiety Disorders: a Review of the Literature
Current Psychiatry Reviews Therapeutic Approaches to Modulating Glutathione Levels as a Pharmacological Strategy in Alzheimer`s Disease
Current Alzheimer Research Multiple Sclerosis, Gut Microbiota and Permeability: Role of Tryptophan Catabolites, Depression and the Driving Down of Local Melatonin
Current Pharmaceutical Design Oxidative and Inflammatory Events in Prion Diseases: Can They Be Therapeutic Targets?
Current Aging Science Clinical, Genetic, and Neuroimaging Features of Early Onset Alzheimer Disease: The Challenges of Diagnosis and Treatment
Current Alzheimer Research Meet Our Editorial Board Member
Mini-Reviews in Medicinal Chemistry Conference Report: (13th International Congress on Amino Acids, Peptides and Proteins (ICAPP); Neurobiology Symposium, October 5-7, 2013; Galveston TX, USA.)
CNS & Neurological Disorders - Drug Targets Mathematical Nanotoxicoproteomics: Quantitative Characterization of Effects of Multi-walled Carbon Nanotubes (MWCNT) and TiO2 Nanobelts (TiO2-NB) on Protein Expression Patterns in Human Intestinal Cells
Current Computer-Aided Drug Design Review of Interventions for Parental Depression from Toddlerhood to Adolescence
Current Psychiatry Reviews When “Chems” Meet Sex: A Rising Phenomenon Called “ChemSex”
Current Neuropharmacology Meet Our Section Editor
Current Medicinal Chemistry Alternate Strategies of Hsp90 Modulation for the Treatment of Cancer and Other Diseases
Current Topics in Medicinal Chemistry Early Pathogenesis of Atherosclerosis: The Childhood Obesity
Current Pharmaceutical Design Editorial [ Hot Topic: Drugs Targets in Parkinson's Disease:Where Are We and Where should We Go? (Guest Editor: Mark R. Cookson)]
CNS & Neurological Disorders - Drug Targets Application of Functional Genomics and Proteomics to Plant Cryopreservation
Current Genomics Oxidative Status in Multiple Sclerosis and Off-Targets of Antioxidants: The Case of Edaravone
Current Medicinal Chemistry Elucidation of Abnormal Extracellular Regulated Kinase (ERK) Signaling and Associations with Syndromic and Non-syndromic Autism
Current Drug Targets Histaminergic Control of Sleep-Wake Cycles: Recent Therapeutic Advances for Sleep and Wake Disorders
CNS & Neurological Disorders - Drug Targets Harnessing Metabolomics for Nutrition Research
Current Pharmaceutical Biotechnology