Abstract
The use of polymers in different fields of modern medicine has generated significant advances in tissue engineering, diagnostic and therapeutic strategies. Polymers have been used to control the rate of drug release, prevent toxicity, protect drugs from degradation before delivery, target drugs to the site of action, improve absorption, bioavailability and therapeutic efficacy. Although synthetic polymers allow producing tailor-made materials, however natural polymers exhibit the advantages of excellent biodegradability, biocompatibility, cost-effectiveness and environmental friendliness. This review presents the current status of research and clinical applications of natural polymers as drug delivery systems for different administration routes.
Keywords: Natural polymers, proteins, polysaccharides, drug delivery, mucosal delivery, enteral delivery, central nervous system delivery.
Current Organic Chemistry
Title:Biomedical Applications of Natural Polymers for Drug Delivery
Volume: 18 Issue: 2
Author(s): Mariana Carmen Chifiriuc, Alexandru Mihai Grumezescu, Valentina Grumezescu, Eugenia Bezirtzoglou, Veronica Lazar and Alexandra Bolocan
Affiliation:
Keywords: Natural polymers, proteins, polysaccharides, drug delivery, mucosal delivery, enteral delivery, central nervous system delivery.
Abstract: The use of polymers in different fields of modern medicine has generated significant advances in tissue engineering, diagnostic and therapeutic strategies. Polymers have been used to control the rate of drug release, prevent toxicity, protect drugs from degradation before delivery, target drugs to the site of action, improve absorption, bioavailability and therapeutic efficacy. Although synthetic polymers allow producing tailor-made materials, however natural polymers exhibit the advantages of excellent biodegradability, biocompatibility, cost-effectiveness and environmental friendliness. This review presents the current status of research and clinical applications of natural polymers as drug delivery systems for different administration routes.
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Chifiriuc Carmen Mariana, Grumezescu Mihai Alexandru, Grumezescu Valentina, Bezirtzoglou Eugenia, Lazar Veronica and Bolocan Alexandra, Biomedical Applications of Natural Polymers for Drug Delivery, Current Organic Chemistry 2014; 18 (2) . https://dx.doi.org/10.2174/138527281802140129104525
DOI https://dx.doi.org/10.2174/138527281802140129104525 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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