Abstract
The primary contact between the fungal phytopathogen Botrytis cinerea and its host takes place at the cell surface of both organisms. The fungal cell wall is generally composed of an inner skeletal layer consisting of various polysaccharides surrounded by a layer of glycoproteins. Some of these glycoproteins have structural or enzymatic functions, or are involved in conidial adhesion. After landing on the host surface and sensing appropriate signals, B. cinerea conidia produce a germ tube and secrete phytotoxic fungal metabolites and cell wall-degrading enzymes (CWDEs), facilitating host penetration. In fact, 118 genes encoding putative Carbohydrate-Active Enzymes (CAZymes) have been identified in the B. cinerea genome. This large enzymatic repertoire could explain, at least in part, the ability of B. cinerea to infect a vast number of plant species. In recent years, several genes and signaling factors have been identified as playing key roles in pathogenesis, particularly in appressorium formation and penetration. These include the NOX Complex, MAPK cascades, heterotrimeric G proteins, histidine kinases and cAMP signaling pathways. Some of these pathways could also be responsible for controlling the expression and secretion of CWDEs and/or secondary metabolites during infection. Herein, putative virulence factors that are linked to the cell wall, as well as recentlydescribed genes and components that allow the sensing of environmental cues, are highlighted.
Keywords: Botrytis cinerea, cell wall, virulence factor, cell wall-degrading enzymes, light, circadian clock.
Current Protein & Peptide Science
Title:Recent Advances in the Study of the Plant Pathogenic Fungus Botrytis cinerea and its Interaction with the Environment
Volume: 18 Issue: 10
Author(s): Luis Castillo*, Verónica Plaza, Luis F. Larrondo and Paulo Canessa
Affiliation:
- Laboratory of Biochemistry and Molecular Biology, Department of Biology, Faculty of Sciences, University of La Serena, La Serena,Chile
Keywords: Botrytis cinerea, cell wall, virulence factor, cell wall-degrading enzymes, light, circadian clock.
Abstract: The primary contact between the fungal phytopathogen Botrytis cinerea and its host takes place at the cell surface of both organisms. The fungal cell wall is generally composed of an inner skeletal layer consisting of various polysaccharides surrounded by a layer of glycoproteins. Some of these glycoproteins have structural or enzymatic functions, or are involved in conidial adhesion. After landing on the host surface and sensing appropriate signals, B. cinerea conidia produce a germ tube and secrete phytotoxic fungal metabolites and cell wall-degrading enzymes (CWDEs), facilitating host penetration. In fact, 118 genes encoding putative Carbohydrate-Active Enzymes (CAZymes) have been identified in the B. cinerea genome. This large enzymatic repertoire could explain, at least in part, the ability of B. cinerea to infect a vast number of plant species. In recent years, several genes and signaling factors have been identified as playing key roles in pathogenesis, particularly in appressorium formation and penetration. These include the NOX Complex, MAPK cascades, heterotrimeric G proteins, histidine kinases and cAMP signaling pathways. Some of these pathways could also be responsible for controlling the expression and secretion of CWDEs and/or secondary metabolites during infection. Herein, putative virulence factors that are linked to the cell wall, as well as recentlydescribed genes and components that allow the sensing of environmental cues, are highlighted.
Export Options
About this article
Cite this article as:
Castillo Luis*, Plaza Verónica, Larrondo F. Luis and Canessa Paulo, Recent Advances in the Study of the Plant Pathogenic Fungus Botrytis cinerea and its Interaction with the Environment, Current Protein & Peptide Science 2017; 18 (10) . https://dx.doi.org/10.2174/1389203717666160809160915
DOI https://dx.doi.org/10.2174/1389203717666160809160915 |
Print ISSN 1389-2037 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5550 |
Call for Papers in Thematic Issues
Advancements in Proteomic and Peptidomic Approaches in Cancer Immunotherapy: Unveiling the Immune Microenvironment
The scope of this thematic issue centers on the integration of proteomic and peptidomic technologies into the field of cancer immunotherapy, with a particular emphasis on exploring the tumor immune microenvironment. This issue aims to gather contributions that illustrate the application of these advanced methodologies in unveiling the complex interplay ...read more
Artificial Intelligence for Protein Research
Protein research, essential for understanding biological processes and creating therapeutics, faces challenges due to the intricate nature of protein structures and functions. Traditional methods are limited in exploring the vast protein sequence space efficiently. Artificial intelligence (AI) and machine learning (ML) offer promising solutions by improving predictions and speeding up ...read more
Nutrition and Metabolism in Musculoskeletal Diseases
The musculoskeletal system consists mainly of cartilage, bone, muscles, tendons, connective tissue and ligaments. Balanced metabolism is of vital importance for the homeostasis of the musculoskeletal system. A series of musculoskeletal diseases (for example, sarcopenia, osteoporosis) are resulted from the dysregulated metabolism of the musculoskeletal system. Furthermore, metabolic diseases (such ...read more
Protein Folding, Aggregation and Liquid-Liquid Phase Separation
Protein folding, misfolding and aggregation remain one of the main problems of interdisciplinary science not only because many questions are still open, but also because they are important from the point of view of practical application. Protein aggregation and formation of fibrillar structures, for example, is a hallmark of a ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Cycloxygenase-2 (COX-2) - A Potential Target for Screening of Small Molecules as Radiation Countermeasure Agents: An In Silico Study
Current Computer-Aided Drug Design The Vanilloid Agonist Resiniferatoxin for Interventional-Based Pain Control
Current Topics in Medicinal Chemistry Development and Evaluation of Solid Self-Microemulsifying Drug Delivery System of Aceclofenac Using Neusilin
Current Nanomedicine Complement and Complement Regulatory Proteins as Potential Molecular Targets for Vascular Diseases
Current Pharmaceutical Design Statins for Diabetic Cardiovascular Complications
Current Vascular Pharmacology Natural Products with Analgesic Effect from Herbs and Nutraceuticals Used in Traditional Chinese Medicines
Current Molecular Medicine Targeted Therapy of Breast Cancer
Current Pharmaceutical Design Natural Tregs in Systemic Lupus Erythematosus
Current Immunology Reviews (Discontinued) Radiosensitizing Potential of Epigenetic Anticancer Drugs
Anti-Cancer Agents in Medicinal Chemistry Prolonged NHE Activation may be both Cause and Outcome of Cytokine Release Syndrome in COVID-19
Current Pharmaceutical Design Regulation of Blood Flow by Prostaglandins
Current Vascular Pharmacology Prophylactic Admission of an In Vitro Reconstructed Complexes of Human Recombinant Heat Shock Proteins and Melanoma Antigenic Peptides Activates Anti-Melanoma Responses in Mice
Current Molecular Medicine Patent Selections:
Recent Patents on Drug Delivery & Formulation Toll-Like Receptors: Sensor Molecules for Detecting Damage to the Nervous System
Current Protein & Peptide Science Salicylates and their Spectrum of Activity
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry DNA Repair Proteins as Molecular Targets for Cancer Therapeutics
Anti-Cancer Agents in Medicinal Chemistry Anti-Cancer
Current Bioactive Compounds Chronic Eosinophilic Leukemia, Not Otherwise Specified (CEL, NOS)
Current Cancer Therapy Reviews HPV-mediated Cervical Cancer: A Systematic Review on Immunological Basis, Molecular Biology, and Immune Evasion Mechanisms
Current Drug Targets Stilbenes and Xanthones from Medicinal Plants as Potential Antitumor Agents
Current Bioactive Compounds