Abstract
The spatial ordering information of amino acid residue in protein primary sequence is an important determinant of protein three-dimensional structure. In this paper, we describe a radial basis function neural network (RBFNN), whose hidden centers and basis function widths are optimized by a genetic algorithm (GA), for the purpose of predicting three dimensional spatial distance location from primary sequence information. Experimental evidence on soybean protein sequences indicates the utility of this approach.
Keywords: spatial distance, radial basis function neural network, genetic algorithm, soybean protein, prediction
Protein & Peptide Letters
Title: Inter-Residue Spatial Distance Map Prediction by Using Integrating Ga with Rbfnn
Volume: 11 Issue: 6
Author(s): Guang-Zheng Zhang and De-Shuang Huang
Affiliation:
Keywords: spatial distance, radial basis function neural network, genetic algorithm, soybean protein, prediction
Abstract: The spatial ordering information of amino acid residue in protein primary sequence is an important determinant of protein three-dimensional structure. In this paper, we describe a radial basis function neural network (RBFNN), whose hidden centers and basis function widths are optimized by a genetic algorithm (GA), for the purpose of predicting three dimensional spatial distance location from primary sequence information. Experimental evidence on soybean protein sequences indicates the utility of this approach.
Export Options
About this article
Cite this article as:
Zhang Guang-Zheng and Huang De-Shuang, Inter-Residue Spatial Distance Map Prediction by Using Integrating Ga with Rbfnn, Protein & Peptide Letters 2004; 11 (6) . https://dx.doi.org/10.2174/0929866043406283
DOI https://dx.doi.org/10.2174/0929866043406283 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers