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Mini-Review Article

Status of α-emitter Radioimmunoconjugates for Targeted Therapy

Author(s): Rabiei Mobina, Ahmad Reza Vaez Alaei and Hassan Yousefnia*

Volume 16, Issue 2, 2023

Published on: 10 February, 2023

Page: [85 - 94] Pages: 10

DOI: 10.2174/1874471016666230106111119

Price: $65

Abstract

This minireview describes the global situation of ongoing research and development and the clinical application of alpha emitter labeled immunoconjugates with various alpha emitters with an overview of the future trends. The potentially helpful alpha emitter radioisotopes for medical applications, chelators, and immunomolecules of interest for future alpha radioimmunotherapy are discussed. Challenges and some suggested future works on chelators are also presented.

Keywords: α-emitters, radio, immunotherapy, immunoconjugates, bifunctional ligands, trials.

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