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Current Pediatric Reviews


ISSN (Print): 1573-3963
ISSN (Online): 1875-6336

Review Article

Fresh Frozen Plasma Administration in the NICU: Evidence-based Guidelines

Author(s): Mario Motta* and Brunetta Guaragni

Volume 19, Issue 4, 2023

Published on: 22 December, 2022

Page: [342 - 351] Pages: 10

DOI: 10.2174/1573396319666221219153009

Price: $65


The use of FFP in neonatology should be primarily for neonates with active bleeding and associated coagulopathy. However, since there is limited and poor-quality evidence supporting neonatal FFP transfusion, considerable FFP usage continues to be outside of this recommendation, as documented by neonatal transfusion audits. This review updates the scientific evidence available on FFP use in neonatology and reports the best evidence-practice for the safety of neonates receiving FFP.

Keywords: Fresh frozen plasma, transfusion, neonatology, coagulation tests, bleeding, neonate.

Graphical Abstract
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