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Protein & Peptide Letters

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Mini-Review Article

Are Bacteriocins a Feasible Solution for Current Diverse Global Problems?

Author(s): Cristóbal Joel González-Pérez , Emmanuel Aispuro-Hernández, Irasema Vargas-Arispuro, Adrián Hernández-Mendoza , Jesús Fernando Ayala-Zavala and Miguel Ángel Martínez-Téllez*

Volume 28, Issue 12, 2021

Published on: 08 October, 2021

Page: [1330 - 1337] Pages: 8

DOI: 10.2174/0929866528666211008154430

Price: $65

Abstract

Abstract: The development of effective technologies to cope with persistent and progressive global problems in human health and sustainable development has become an imperative worldwide challenge. The search for natural alternatives has led to the discovery of bacteriocins, which are potent protein antimicrobial compounds produced by most bacteria. The relevance of these molecules is evidenced by more than 4,500 papers published in the last decade in Scopus indexed journals highlighting their versatility and potential to impact various aspects of daily life, including the food industry, medicine, and agriculture. Bacteriocins have demonstrated antibacterial, antifungal, antiviral, and anticancer activities, and they also act as microbiota regulators and plant growth promoters. This mini-review aims to provide insights into the current state and emerging roles of bacteriocins, as well as their potential and limitations as feasible solutions against current diverse global problems.

Keywords: Bacteriocin secretion pathways, toxicity of bacteriocins, anticancer agent, antiviral agent, microbiota regulator, plant growth promoter.

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