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Current Medicinal Chemistry
ISSN (Print): 0929-8673
ISSN (Online): 1875-533X
VOLUME: 10
ISSUE: 21
DOI: 10.2174/0929867033456710      Price:  $58









An Over Four Millennium Story Behind Qinghaosu (Artemisinin)-A Fantastic Antimalarial Drug from a Traditional Chinese Herb

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Author(s): Ying Li and Yu-Lin Wu
Pages 2197-2230 (34)
Abstract:
This article reviews the discovery and the further studies on qinghaosu and its derivatives or analogs over the last decades in the fields of medicinal chemistry and some pharmacology research, with an emphasis on the progress achieved in China.
Keywords:
artemisinin, chemistry, structure determination, synthesis, pharmacology, antimalarial, mechanism of action
Affiliation:
State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of OrganicChemistry, Chinese Academy of Sciences, 354 FengLin Road, Shanghai 200032, China.