Search Result "tubulin polymerization"


Research Article

Concise Synthesis of 1,1-Diarylvinyl Sulfones and Investigations on their Antiproliferative Activity via Tubulin Inhibition

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 20 Issue: 1 Year: 2020 Page: 1469-1474
Author(s): Lavanya Reddy,Suja T. Dharmabalan,Kanakaraju Manupati,Ragini Yeeravalli,Lakshmi D. Vijay,Kavitha Donthiboina,Vadithe Lakshma Naik,Amitava Das

Research Article

Synthesis of N-acyl Derivatives of Aminocombretastatin A-4 and Study of their Interaction with Tubulin and downregulation of c-Myc

Journal: Medicinal Chemistry
Volume: 16 Issue: 0 Year: 2020 Page: 1-14
Author(s): Raül Agut,Eva Falomir,Juan Murga,Celia Martín-Beltrán,Raquel Gil-Edo,Alberto Pla,Miguel Carda,J. Fernando Díaz,Fernando Josa-Prado,J. Alberto Marco

General Review Article

Tubulin Maytansine Site Binding Ligands and Their Applications as MTAs and ADCs for Cancer Therapy

Journal: Current Medicinal Chemistry
Volume: 27 Issue: 2 Year: 2020 Page: 4567-4576
Author(s): Shuo Cao,Yue-Hui Dong,De-Feng Wang,Zhao-Peng Liu

Research Article

Towards further Understanding the Structural Requirements of Combretastatin- like Chalcones as Inhibitors of Microtubule Polymerization

Journal: Current Computer-Aided Drug Design
Volume: 16 Issue: 2 Year: 2020 Page: 155-166
Author(s): Naveen Dhingra,Anand Kar,Rajesh Sharma

Research Article

Biological Evaluation and Molecular Modeling of 3,4-dihydropyrimidine- 2(1H)-one Derivatives as Cytotoxic Agents on Breast Cancer In Vitro

Journal: Letters in Drug Design & Discovery
Volume: 17 Issue: 8 Year: 2020 Page: 983-992
Author(s): Hoda Sharifi,Ahmad Ebadi,Meysam Soleimani

Research Article

Antiproliferative Activity of 8-methoxy Ciprofloxacin-Hydrozone/Acylhydrazone Scaffolds

Journal: Current Topics in Medicinal Chemistry
Volume: 20 Issue: 2 Year: 2020 Page: 1911-1915
Author(s): Li-Ping Wang,Zhi Xu,Gui-Ying Deng,Sha-Li Xu

Research Article

Design, Synthesis and In-vitro Anti-Cancer Evaluation of Novel Derivatives of 2-(2-Methyl-1,5-diaryl-1H-pyrrol-3-yl)-2-oxo-N-(pyridin-3-yl)acetamide

Journal: Medicinal Chemistry
Volume: 16 Issue: 3 Year: 2020 Page: 340-349
Author(s): Ebrahim Saeedian Moghadam,Farhad Saravani,Ernest Hamel,Zahra Shahsavari,Mohsen Alipour,Saman Hosseinkhani,Seyednasser Ostad,Mohsen Amini

Research Article

Evaluation of Anticancer and Anti-mitotic Properties of Quinazoline and Quinazolino-Benzothiadiazine Derivatives

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 20 Issue: 5 Year: 2020 Page: 599-611
Author(s): Thoukhir B. Shaik,Ahmed Kamal,M. Shaheer Malik,Sunitha R. Routhu,Zaki S. Seddigi,Ismail I. Althagafi

Research Article

Moxifloxacin-isatin Hybrids Tethered by 1,2,3-triazole and their Anticancer Activities

Journal: Current Topics in Medicinal Chemistry
Volume: 20 Issue: 1 Year: 2020 Page: 1461-1467
Author(s): Mingli Yang,Hailin Liu,Yazhou Zhang,Xiujun Wang,Zhi Xu

Review Article

Lipid-based Nanoplatforms in Cancer Therapy: Recent Advances and Applications

Journal: Current Cancer Drug Targets
Volume: 20 Issue: 4 Year: 2020 Page: 271-287
Author(s): Kuldeep Rajpoot

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