Search Result "hit identification."


Increasing the Odds of Drug Hit Identification by Screening Against Receptor Homologs?

Journal: Letters in Drug Design & Discovery
Volume: 3 Issue: 3 Year: 2006 Page: 200-204
Author(s): Z. L. Ji, Z. R. Li, J. F. Wang, C. Z. Cai, L. Y. Han, C. J. Zheng, Y. Z. Chen

Rational Design Approaches to Chemical Libraries for Hit Identification

Journal: Current Drug Discovery Technologies
Volume: 3 Issue: 1 Year: 2006 Page: 49-65
Author(s): Konstantin V. Balakin, Alexander V. Kozintsev, Alex S. Kiselyov, Nikolay P. Savchuk

A Collaborative Hit-to-Lead Investigation Leveraging Medicinal Chemistry Expertise with High Throughput Library Design, Synthesis and Purification Capabilities

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 2 Year: 2006 Page: 123-130
Author(s): X. Yang, D. Parker, L. Whitehead, N. S. Ryder, B. Weidmann, M. Stabile-Harris, D. Kizer, M. McKinnon, A. Smellie, D. Powers

NMR-Based Quality Control Approach for the Identification of False Positives and False Negatives in High Throughput Screening

Journal: Current Drug Discovery Technologies
Volume: 3 Issue: 2 Year: 2006 Page: 115-124
Author(s): Claudio Dalvit, Dannica Caronni, Nicola Mongelli, Marina Veronesi, Anna Vulpetti

The Nuclear Overhauser Effect in the Lead Identification Process Pharmacophore Models

Journal: Current Drug Discovery Technologies
Volume: 3 Issue: 2 Year: 2006 Page: 91-100
Author(s): Marilisa Leone, Hudson H. Freeze, Chui Sien Chan, Maurizio Pellecchia

Computational Methods for Analysis of High-Throughput Screening Data

Journal: Current Computer-Aided Drug Design
Volume: 2 Issue: 1 Year: 2006 Page: 1-19
Author(s): Konstantin V. Balakin, Nikolay P. Savchuk

Recent Developments in Focused Library Design: Targeting Gene-Families

Journal: Current Topics in Medicinal Chemistry
Volume: 6 Issue: 1 Year: 2006 Page: 19-29
Author(s): Jennifer L. Miller

Discovery of New Small Molecules and Targets Towards Angiogenesis Via Chemical Genomics Approach

Journal: Current Drug Targets
Volume: 7 Issue: 4 Year: 2006 Page: 397-405
Author(s): Ho J. Kwon

Rethinking Target Discovery in Polygenic Diseases

Journal: Current Topics in Medicinal Chemistry
Volume: 6 Issue: 1 Year: 2006 Page: 1791-1798
Author(s): Christodoulos S. Flordellis, Antonis S. Manolis, Herve Paris, Andreas Karabinis

Design and Characterization of a Functional Library for NMR Screening Against Novel Protein Targets

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 7 Year: 2006 Page: 515-534
Author(s): Robert Powers, Katherine Germer, Kelly A. Mercier

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