Search Result "half-lives"


Targeted Delivery of Short Interfering RNAs - Strategies for In Vivo Delivery

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 4 Issue: 1 Year: 2009 Page: 1-8
Author(s): Ulrich Wullner, Inga Neef, Mehmet K. Tur, Stefan Barth

Synthesis and In Vitro Transdermal Penetration of Methoxypoly(ethylene glycol) Carbonate Derivatives of Stavudine

Journal: Medicinal Chemistry
Volume: 5 Issue: 6 Year: 2009 Page: 497-506
Author(s): David D. NDa, Jaco C. Breytenbach, Lesetja J. Legoabe, J. Wilma Breytenbach

Innovations and Opportunities to Improve Conventional (Deoxy)Nucleoside and Fluoropyrimidine Analogs in Cancer

Journal: Current Medicinal Chemistry
Volume: 16 Issue: 3 Year: 2009 Page: 4632-4643
Author(s): A. D. Adema, I. V. Bijnsdorp, M. L. Sandvold, H. M. Verheul, G. J. Peters

The Potential of Modulating Small RNA Activity In Vivo

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 9 Issue: 2 Year: 2009 Page: 235-248
Author(s): Alain van Mil, Pieter A. Doevendans, Joost P.G. Sluijter

Microdosing, Imaging Biomarkers and SPECT: A Multi-Sided Tripod to Accelerate Drug Development

Journal: Current Pharmaceutical Design
Volume: 15 Issue: 9 Year: 2009 Page: 928-934
Author(s): Ernest K.J. Pauwels, Kim Bergstrom, Giuliano Mariani, Kalevi Kairemo

High Throughput Quantitative Assessment of CYP Inactivation Using 2 Concentration Points

Journal: Drug Metabolism Letters
Volume: 3 Issue: 2 Year: 2009 Page: 78-82
Author(s): Daniel Albaugh, Thomas Farrell, Michael Langan, W. George Lai

Instrumental Considerations in High Content Screening

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 12 Issue: 9 Year: 2009 Page: 888-898
Author(s): Chris Shumate, Ann F. Hoffman

Production and Application of Copper Radiopharmaceuticals

Journal: Current Radiopharmaceuticals
Volume: 2 Issue: 2 Year: 2009 Page: 92-101
Author(s): Amir Reza Jalilian, Pejman Rowshanfarzad, Mahsheed Sabet

Structure-Activity Relationship (SAR): Effort Towards Blocking NGlucuronidation of Indazoles (PF-03376056) By Human UGT1A Enzymes

Journal: Drug Metabolism Letters
Volume: 3 Issue: 1 Year: 2009 Page: 28-34
Author(s): Kelly Rose, Young-Sun Yang, Richard Sciotti, Hongliang Cai

Seeing Genes at Work in the Living Brain with Non-Invasive Molecular Imaging

Journal: Current Gene Therapy
Volume: 9 Issue: 3 Year: 2009 Page: 212-238
Author(s): Christophe M. Deroose, Veerle Reumers, Zeger Debyser, Veerle Baekelandt

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