Search Result "Structure based drug design"


Ligand-Based Drug Design Methodologies in Drug Discovery Process: An Overview

Journal: Current Drug Discovery Technologies
Volume: 3 Issue: 3 Year: 2006 Page: 155-165
Author(s): Magdalena Bacilieri, Stefano Moro

Targeting Cancer: The Challenges and Successes of Structure-Based Drug Design Against the Human Purinome

Journal: Current Topics in Medicinal Chemistry
Volume: 6 Issue: 1 Year: 2006 Page: 1129-1159
Author(s): Mark Knapp, Cornelia Bellamacina, Jeremy M. Murray, Dirksen E. Bussiere

Structural Biology and Drug Discovery

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 1 Year: 2006 Page: 2087-2097
Author(s): Giovanna Scapin

Computational Approaches to Model Ligand Selectivity in Drug Design

Journal: Current Topics in Medicinal Chemistry
Volume: 6 Issue: 1 Year: 2006 Page: 41-55
Author(s): Angel R. Ortiz, Paulino Gomez-Puertas, Alejandra Leo-Macias, Pedro Lopez-Romero, Eduardo Lopez-Vinas, Antonio Morreale, Marta Murcia, Kun Wang

Rational Design Approaches to Chemical Libraries for Hit Identification

Journal: Current Drug Discovery Technologies
Volume: 3 Issue: 1 Year: 2006 Page: 49-65
Author(s): Konstantin V. Balakin, Alexander V. Kozintsev, Alex S. Kiselyov, Nikolay P. Savchuk

Methods for the Prediction of Protein-Ligand Binding Sites for Structure-Based Drug Design and Virtual Ligand Screening.

Journal: Current Protein & Peptide Science
Volume: 7 Issue: 5 Year: 2006 Page: 395-406
Author(s):

Signal Transduction Therapy with Rationally Designed Kinase Inhibitors

Journal: Current Signal Transduction Therapy
Volume: 1 Issue: 1 Year: 2006 Page: 67-95
Author(s): Gyorgy Keri, Laszlo Orfi, Daniel Eros, Balint Hegymegi-Barakonyi, Csaba Szantai-Kis, Zoltan Horvath, Frigyes Waczek, Jeno Marosfalvi, Istvan Szabadkai, Janos Pato, Zoltan Greff, Doris Hafenbradl, Henrik Daub, Gerhard Muller, Bert Klebl, Axel Ullrich

Structure- and Fragment-Based Approaches to Protease Inhibition

Journal: Current Topics in Medicinal Chemistry
Volume: 6 Issue: 4 Year: 2006 Page: 317-329
Author(s): Sherida L. Johnson, Maurizio Pellecchia

Structural Properties of the NMDA Receptor and the Design of Neuroprotective Therapies

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 6 Issue: 7 Year: 2006 Page: 805-815
Author(s): A. M. Gerber, M. L. Vallano

Quaternary Structure, Substrate Selectivity and Inhibitor Design for SARS 3C-Like Proteinase

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 3 Year: 2006 Page: 4555-4564
Author(s): Luhua Lai, Xiaofeng Han, Hao Chen, Ping Wei, Changkang Huang, Shiyong Liu, Keqiang Fan, Lu Zhou, Zhenming Liu, Jianfeng Pei, Ying Liu

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