Search Result "Optimization"


Application and Utilization of Chemoinformatics Tools in Lead Generation and Optimization

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 2 Year: 2006 Page: 95-102
Author(s): N. Fotouhi, P. Gillespie, R. A. Goodnow, S.- S. So, Y. Han, L. E. Babiss

A Method for Rapid Protease Substrate Evaluation and Optimization

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 6 Year: 2006 Page: 481-487
Author(s): Igor A. Kozlov, Peter C. Melnyk, Chanfeng Zhao, John P. Hachmann, Veronika Shevchenko, Anu Srinivasan, David L. Barker, Michal Lebl

Optimization of Small Molecule Drugs Binding to Highly Polar Target Sites: Lessons from the Discovery and Development of Neuraminidase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 6 Issue: 5 Year: 2006 Page: 423-434
Author(s): Klaus Klumpp, Bradford J. Graves

Promotion of Optimized Protein Therapy by Bioconjugation as a Polymeric DDS

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 6 Issue: 3 Year: 2006 Page: 251-258
Author(s): Yasuhiro Abe, Hiroko Shibata, Haruhiko Kamada, Shin-Ichi Tsunoda, Yasuo Tsutsumi, Shinsaku Nakagawa

Development and Optimization of a Non-Radioactive JNK3 Assay

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 8 Year: 2006 Page: 613-618
Author(s): Christian Peifer, Sabine Luik, Sabine Thuma, Yvonne Herweh, Stefan Laufer

Barriers to Achieving Optimal Glycemic Control in a Multi-Ethnic Society: A US Focus

Journal: Current Diabetes Reviews
Volume: 2 Issue: 3 Year: 2006 Page: 285-293
Author(s): Samuel Dagogo-Jack, Martha M. Funnell, Jaime Davidson

Optimizing a Biocatalyst for Improved NAD(P)H Regeneration: Directed Evolution of Phosphite Dehydrogenase

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 4 Year: 2006 Page: 237-245
Author(s): Ryan Woodyer, Wilfred A. van der Donk, Huimin Zhao

Nebulizer Therapy in Pulmonology: Review of the Literature

Journal: Current Respiratory Medicine Reviews
Volume: 2 Issue: 2 Year: 2006 Page: 211-235
Author(s): Andrea S. Melani, Letizia S. Bracci

The Monomers of the P2X1 Receptor Model and KcsA Protein Share a Similar Structural Fold.

Journal: Protein & Peptide Letters
Volume: 13 Issue: 1 Year: 2006 Page: 77-81
Author(s): P. P. Mager, A. Weber, L. Sanchez, K. Wirkner, P. Illes

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