Search Result "MAP-kinases"


Statin Attenuates High Glucose-Induced and Angiotensin II-Induced MAP Kinase Activity Through Inhibition of NAD(P)H Oxidase Activity in Cultured Mesangial Cells

Journal: Medicinal Chemistry
Volume: 1 Issue: 5 Year: 2005 Page: 461-468
Author(s): H. Y. Yu, T. Inoguchi, M. Nakayama, H. Tsubouchi, N. Sato, N. Sonoda, S. Sasaki, K. Kobayashi, H. Nawata

Potential Adverse Effects Associated with Inhibition of p38α/β MAP Kinases

Journal: Current Topics in Medicinal Chemistry
Volume: 5 Issue: 1 Year: 2005 Page: 929-939
Author(s): Donna M. Dambach

Pathway to the Clinic: Inhibition of P38 MAP Kinase. A Review of Ten Chemotypes Selected for Development

Journal: Current Topics in Medicinal Chemistry
Volume: 5 Issue: 1 Year: 2005 Page: 1017-1029
Author(s): David M. Goldstein, Tobias Gabriel

Targeting Chk2 Kinase: Molecular Interaction Maps and Therapeutic Rationale

Journal: Current Pharmaceutical Design
Volume: 11 Issue: 2 Year: 2005 Page: 2855-2872
Author(s): Y. Pommier, O. Sordet, A. Rao, H. Zhang, K. W. Kohn

MAP Kinase p38Inhibitors: Clinical Results and an Intimate Look at Their Interactions with p38α Protein

Journal: Current Medicinal Chemistry
Volume: 12 Issue: 2 Year: 2005 Page: 2979-2994
Author(s): Matthew R. Lee, Celia Dominguez

P38 MAP Kinase Inhibitors: Evolution of Imidazole-Based and Pyrido- Pyrimidin-2-One Lead Classes

Journal: Current Topics in Medicinal Chemistry
Volume: 5 Issue: 1 Year: 2005 Page: 987-1003
Author(s): Swaminathan R. Natarajan, James B. Doherty

Structure-Activity Relationships of p38 Mitogen-Activated Protein Kinase Inhibitors

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 5 Issue: 9 Year: 2005 Page: 857-868
Author(s): Jordi Bolos

Structural Comparison of p38 Inhibitor-Protein Complexes: A Review of Recent p38 Inhibitors Having Unique Binding Interactions

Journal: Current Topics in Medicinal Chemistry
Volume: 5 Issue: 1 Year: 2005 Page: 1005-1016
Author(s): Stephen T. Wrobleski, Arthur M. Doweyko

Progress Towards Therapeutic Small Molecule MEK Inhibitors for Use in Cancer Therapy

Journal: Current Topics in Medicinal Chemistry
Volume: 5 Issue: 2 Year: 2005 Page: 215-229
Author(s): Eli M. Wallace, Joseph P. Lyssikatos, Tammie Yeh, James D. Winkler, Kevin Koch

Pharmacological Approaches of Neurofibrillary Degeneration

Journal: Current Alzheimer Research
Volume: 2 Issue: 3 Year: 2005 Page: 335-341
Author(s): Khalid Iqbal, Inge Grundke-Iqbal

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