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Targeting JAK3 Tyrosine Kinase-Linked Signal Transduction Pathways with Rationally-Designed Inhibitors

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 7 Issue: 6 Year: 2007 Page: 612-623
Author(s): Fatih M. Uckun, Alexei Vassilev, Ilker Dibirdik, Heather Tibbles

In Silico Design of Protein Kinase Inhibitors: Successes and Failures

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 7 Issue: 2 Year: 2007 Page: 171-188
Author(s): Galina G. Dubinina, Oleksandr O. Chupryna, Maxim O. Platonov, Petro O. Borisko, Galina V. Ostrovska, Andriy O. Tolmachov, Alexander A. Shtil

Role of Endogenous Inhibitors of Cytokine Signaling in Allergic Asthma

Journal: Current Medicinal Chemistry
Volume: 14 Issue: 2 Year: 2007 Page: 181-189
Author(s): Hiromasa Inoue, Satoru Fukuyama, Koichiro Matsumoto, Masato Kubo, Akihiko Yoshimura

Targeting Plasminogen Activator Inhibitor-1: Role in Cell Signaling and the Biology of Domain-Specific Knock-in Mice

Journal: Current Drug Targets
Volume: 8 Issue: 9 Year: 2007 Page: 982-995
Author(s): R. D. Balsara, Z. Xu, V. A. Ploplis

Brutons Tyrosine Kinase as a New Therapeutic Target

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 7 Issue: 6 Year: 2007 Page: 624-632
Author(s): Fatih M. Uckun, Heather E. Tibbles, Alexei O. Vassilev

Tyrosine Kinases as Targets for Anti-Inflammatory Therapy

Journal: Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Volume: 6 Issue: 1 Year: 2007 Page: 47-60
Author(s): Teruko Tamura, Alexandra Koch

Tyrosine Kinases as Therapeutic Targets in BCR-ABL Negative Chronic Myeloproliferative Disorders

Journal: Current Drug Targets
Volume: 8 Issue: 2 Year: 2007 Page: 205-216
Author(s): Andreas Reiter, Christoph Walz, Nicholas C. P. Cross

In Vivo Target Validation: Methodology and Case Studies on the Janus Kinase Tyk2

Journal: Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Volume: 6 Issue: 1 Year: 2007 Page: 29-45
Author(s): Christian Gausterer, Mathias Muller, Birgit Strobl

In Vivo Osteoarthritis Target Validation Utilizing Genetically-Modified Mice

Journal: Current Drug Targets
Volume: 8 Issue: 2 Year: 2007 Page: 367-376
Author(s): Sonya S. Glasson

Kinases as Drug Targets in Inflammation: In Vitro and In Vivo Target Validation and Expression Profiling

Journal: Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Volume: 6 Issue: 1 Year: 2007 Page: 19-27
Author(s): Tatjana Clarissa Gust, Arne v. Bonin

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