Search Result "Hepatocyte"


Research Article

Selective Toxicity of Apigenin on Cancerous Hepatocytes by Directly Targeting their Mitochondria

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 16 Issue: 12 Year: 2016 Page: 1576-1586
Author(s): Enayatollah Seydi,Hamid R. Rasekh,Ahmad Salimi,Zhaleh Mohsenifar,Jalal Pourahmad

A Novel Plated Hepatocyte Relay Assay (PHRA) for In Vitro Evaluation of Hepatic Metabolic Clearance of Slowly Metabolized Compounds

Journal: Drug Metabolism Letters
Volume: 10 Issue: 1 Year: 2016 Page: 3-15
Author(s): Chi-Chi Peng,Utkarsh Doshi,Chandra Prakash,Albert P. Li

Research Article

Genipin Inhibits the Induction of Inducible Nitric Oxide Synthase Through the Inhibition of NF-κB Activation in Rat Hepatocytes

Journal: Drug Metabolism Letters
Volume: 10 Issue: 4 Year: 2016 Page: 254-263
Author(s): Richi Nakatake,Takumi Tsuda,Takashi Matsuura,Hirokazu Miki,Hidehiko Hishikawa,Hideyuki Matsushima,Morihiko Ishizaki,Kosuke Matsui,Masaki Kaibori,Mikio Nishizawa,Tadayoshi Okumura,Masanori Kon

Research Article

Strong Induction of Cytochrome P450 1A/3A, But not P450 2B, in Cultured Hepatocytes from Common Marmosets and Cynomolgus Monkeys by Typical Human P450 Inducing Agents

Journal: Drug Metabolism Letters
Volume: 10 Issue: 4 Year: 2016 Page: 244-253
Author(s): Shotaro Uehara,Yasuhiro Uno,Takako Suzuki,Takashi Inoue,Masahiro Utoh,Erika Sasaki,Hiroshi Yamazaki

Research Article

The Uremic Toxin Indoxyl-3-Sulfate Induces CYP1A2 In Primary Human Hepatocytes

Journal: Drug Metabolism Letters
Volume: 10 Issue: 3 Year: 2016 Page: 195-199
Author(s): Hong Liu, Rangaraj Narayanan, Matthew Hoffmann, Sekhar Surapaneni

Targeting Mechanism of a Novel Liver-targeting Interferon IFN-CSP Involves Liver Heparan Sulfate Proteoglycan

Journal: Current Drug Delivery
Volume: 13 Issue: 4 Year: 2016 Page: 528-533
Author(s): Xuemei Lu,Jie Wang,Xiaobao Jin,Yanting Huang,Wenting Zeng,Jiayong Zhu

Bile Acids in Physiology, Pathology and Pharmacology

Journal: Current Drug Metabolism
Volume: 17 Issue: 1 Year: 2016 Page: 4-29
Author(s): Jose J.G. Marin,Rocio I.R. Macias,Oscar Briz,Jesus M. Banales,Maria J. Monte

Microfabricated Devices for Studying the Metabolism and Cytotoxicity of Drug Candidates

Journal: Current Pharmaceutical Biotechnology
Volume: 17 Issue: 9 Year: 2016 Page: 755-771
Author(s): Nathan A. Whitman,Julie C. McIntosh,Jeffrey B. Penley,Matthew R. Lockett

Determination of the Antiproliferative Activity of New Theobromine Derivatives and Evaluation of Their In Vitro Hepatotoxic Effects

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 16 Issue: 7 Year: 2016 Page: 925-932
Author(s): Maya Georgieva,Magdalena Kondeva-Burdina,Javor Mitkov,Virginia Tzankova,Georgi Momekov,Alexander Zlatkov

In vitro Toxicity Evaluation and in vivo Biodistribution of Polymeric Micelles Derived from Poly(ethylene glycol)-b-poly(benzyl malate) Copolymers

Journal: Pharmaceutical Nanotechnology
Volume: 4 Issue: 1 Year: 2016 Page: 24-37
Author(s): Elise Vene,Kathleen Jarnouen,Zhi Wei Huang,Bedhouche Wahib,Tristan Montier,Sandrine Cammas-Marion,Pascal Loyer

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