Search Result "HERG"


Predictive Models for hERG Channel Blockers: Ligand-Based and Structure-Based Approaches

Journal: Current Medicinal Chemistry
Volume: 14 Issue: 2 Year: 2007 Page: 3003-3026
Author(s): Khac-Minh Thai, Gerhard F. Ecker

Lead Optimization Strategies and Tactics Applied to the Discovery of Melanin Concentrating Hormone Receptor 1 Antagonists

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 1471-1488
Author(s): Philip R. Kym, Andrew S. Judd, John K. Lynch, Rajesh Iyengar, Anil Vasudevan, Andrew J. Souers

Computer Prediction of Cardiovascular and Hematological Agents by Statistical Learning Methods

Journal: Cardiovascular & Hematological Agents in Medicinal Chemistry
Volume: 5 Issue: 1 Year: 2007 Page: 11-19
Author(s): X. Chen, H. Li, C. W. Yap, C. Y. Ung, L. Jiang, Z. W. Cao, Y. X. Li, Y. Z. Chen

Novel Anti-Arrhythmic Drugs for Atrial Fibrillation Management

Journal: Current Vascular Pharmacology
Volume: 5 Issue: 3 Year: 2007 Page: 185-194
Author(s): Joachim R. Ehrlich, Stanley Nattel, Stefan H. Hohnloser

Potassium Channels are a New Target Field in Anticancer Drug Design

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 2 Issue: 3 Year: 2007 Page: 212-223
Author(s): Nuria Villalonga, Joan C. Ferrere, Josep M. Argiles, Enric Condom, Antonio Felipe

Automated Electrophysiology in Drug Discovery

Journal: Current Pharmaceutical Design
Volume: 13 Issue: 2 Year: 2007 Page: 2325-2337
Author(s): B.T. Priest, A.M. Swensen, O.B. McManus

New Proposals for Testing Drugs with IKr-Blocking Activity to Determine Their Teratogenic Potential

Journal: Current Pharmaceutical Design
Volume: 13 Issue: 2 Year: 2007 Page: 2979-2988
Author(s): Miriam Karlsson, Bengt R. Danielsson, Mats F. Nilsson, Christian Danielsson, William S. Webster

Preclinical Testing of Drug-Induced Proarrhythmia: Value of Transgenic Models

Journal: Cardiovascular & Hematological Agents in Medicinal Chemistry
Volume: 5 Issue: 4 Year: 2007 Page: 289-294
Author(s): L. Fabritz, G. Breithardt, P. Kirchhof

Structural Development, Haematological Immunological and Pharmacological Effects of Quinolones

Journal: Recent Patents on Anti-Infective Drug Discovery
Volume: 2 Issue: 2 Year: 2007 Page: 157-168
Author(s): Okocha E. Chide, Orish E. Orisakwe

Targeting Ion Channels for New Strategies in Cancer Diagnosis and Therapy

Journal: Current Clinical Pharmacology
Volume: 2 Issue: 2 Year: 2007 Page: 135-144
Author(s): Matteo Conti

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