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Using PBPK Modeling to Predict Drug Exposure and Support Dosage Adjustments in Patients With Renal Impairment: An Example with Lamivudine

Journal: Current Drug Discovery Technologies
Volume: 17 Issue: 3 Year: 2020 Page: 387-396
Author(s): Kushal Shah,Briann Fischetti,Agnes Cha,David R. Taft

Applications of Computer-Aided Pharmacokinetic and Pharmacodynamic Methods from Drug Discovery Through Registration

Journal: Current Computer-Aided Drug Design
Volume: 4 Issue: 1 Year: 2008 Page: 54-66
Author(s): John P. Gibbs, Jennifer Q. Dong, Bin Chen, Megan A. Gibbs, Maurice Emery

PBPK Modeling - A Predictive, Eco-Friendly, Bio-Waiver Tool for Drug Research

Journal: Current Drug Discovery Technologies
Volume: 14 Issue: 3 Year: 2017 Page: 142-155
Author(s): Baishakhi De,Koushik Bhandari,Ranjan Mukherjee,Prakash Katakam,Shanta K. Adiki,Rohit Gundamaraju,Analava Mitra

The Influence of Wuzhi Capsule on the Pharmacokinetics of Cyclophosphamide

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 17 Issue: 2 Year: 2022 Page: 195-203
Author(s): Lu Chen,Ning Ji,Min Zhang,Wanyi Chen

Interplay of Metabolism and Transport in Determining Oral Drug Absorption and Gut Wall Metabolism: A Simulation Assessment Using the “Advanced Dissolution, Absorption, Metabolism (ADAM)” Model

Journal: Current Drug Metabolism
Volume: 11 Issue: 9 Year: 2010 Page: 716-729
Author(s): A. S. Darwich, S. Neuhoff, M. Jamei, A. Rostami-Hodjegan

Journal: Drug Metabolism Letters
Volume: 10 Issue: 3 Year: 2016 Page: 172-179
Author(s): Rangaraj Narayanan, Matthew Hoffmann, Gondi Kumar, Sekhar Surapaneni

Sex Differences in the Clearance of CYP3A4 Substrates: Exploring Possible Reasons for the Substrate Dependency and Lack of Consensus

Journal: Current Drug Metabolism
Volume: 13 Issue: 6 Year: 2012 Page: 778-786
Author(s): Manoranjenni Chetty, Donald Mattison, Amin Rostami-Hodjegan

Scaling Factors for the Extrapolation of In Vivo Metabolic Drug Clearance From In Vitro Data: Reaching a Consensus on Values of Human Micro-somal Protein and Hepatocellularity Per Gram of Liver

Journal: Current Drug Metabolism
Volume: 8 Issue: 1 Year: 2007 Page: 33-45
Author(s): Zoe E. Barter, Martin K. Bayliss, Philip H. Beaune, Alan R. Boobis, David J. Carlile, Robert J. Edwards, J. Brian Houston, Brian G. Lake, John C. Lipscomb, Olavi R. Pelkonen, Geoffrey T. Tucke, Amin Rostami-Hodjegan

Predicting Pediatric Drug Disposition-Present and Future Directions of Pediatric Physiologically-Based Pharmacokinetics

Journal: Drug Metabolism Letters
Volume: 9 Issue: 2 Year: 2015 Page: 80-87
Author(s): Shogo John Miyagi,Janel R. Long-Boyle

In Silico ADMET Prediction: Recent Advances, Current Challenges and Future Trends

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 11 Year: 2013 Page: 1273-1289
Author(s): Feixiong Cheng,Weihua Li,Guixia Liu,Yun Tang