Abstract
Purpose of review: The purpose of this review is to summarize recent advances in the area of genetic polymorphisms in genes affecting immunosuppressive drug bioavailability with a specific emphasis on solid organ transplantation. Recent findings: Due to recent advances in molecular techniques, there has been an abundance of publications describing genetic variability in molecules relevant to pharmacogenetics. The initial studies in the field of transplantation demonstrate some associations between polymorphisms in these candidate genes with outcomes in organ transplantation.
Keywords: Transplantation, genetic polymorphisms, immunosuppressive drug, bioavailability
Current Pharmacogenomics
Title: Genomic Strategies in Transplantation “The Right Drug for the Right Patient”
Volume: 2 Issue: 2
Author(s): Bernd Schroppel
Affiliation:
Keywords: Transplantation, genetic polymorphisms, immunosuppressive drug, bioavailability
Abstract: Purpose of review: The purpose of this review is to summarize recent advances in the area of genetic polymorphisms in genes affecting immunosuppressive drug bioavailability with a specific emphasis on solid organ transplantation. Recent findings: Due to recent advances in molecular techniques, there has been an abundance of publications describing genetic variability in molecules relevant to pharmacogenetics. The initial studies in the field of transplantation demonstrate some associations between polymorphisms in these candidate genes with outcomes in organ transplantation.
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Cite this article as:
Schroppel Bernd, Genomic Strategies in Transplantation “The Right Drug for the Right Patient”, Current Pharmacogenomics 2004; 2 (2) . https://dx.doi.org/10.2174/1570160043377600
DOI https://dx.doi.org/10.2174/1570160043377600 |
Print ISSN 1570-1603 |
Publisher Name Bentham Science Publisher |
Online ISSN 1570-1603 |
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