Generic placeholder image

Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Asymmetric Alkynylation Reactions of Aldehydes Using a Zn(OTf)2-Chiral Ligand-Base System

Author(s): Elizabeth Tyrrell

Volume 13, Issue 15, 2009

Page: [1540 - 1552] Pages: 13

DOI: 10.2174/138527209789177716

Price: $65

Abstract

Optically active propargylic alcohols serve as an important building block in asymmetric synthesis. The customised synthesis of chiral ligands and transition metal activators as catalysts, to effect asymmetric alkynylation reactions, continue to feature in the literature. This review article focuses upon the use of Zn(OTf)2, in conjunction with 2-point chiral ligands, for effecting asymmetric alkynylation reactions to aldehydes.


Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy