Pseudopeptides are privileged synthetic molecules built from the designed combination
of peptide-like and abiotic artificial moieties. Consequently, they are benefited from
the advantages of both families of chemical structures: modular synthesis, chemical and functional
diversity, tailored three-dimensional structure, usually high stability in biological media
and low non-specific toxicity. Accordingly, in the last years, these compounds have been used
for different biomedical applications, ranging from bio-sensing, ion transport, the molecular recognition
of biologically relevant species, drug delivery or gene transfection. This review highlights
a selection of the most remarkable and recent advances in this field.